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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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Issue: May 2024
Volume 9 | Issue 5
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| Paper Title: | A Review on Preparation and Evaluation of Sodium Alginate Beads with Metformin |
| Authors Name: | E. Bunny Priya |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_213277
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| Published Paper Id: | IJNRD2401335 |
| Published In: | Volume 9 Issue 1, January-2024 |
| DOI: | |
| Abstract: | This present study an attempt was made to formulate beads of Metformin Hcl by using Sodium alginate in combination of HPMC , Carbopol ,Pectin and sodium carboxy methyl cellulose. Beads of metformin Hcl were successfully prepared by Ionotropic Gelation Method .The prepared beads evaluated for various parameters lke encapsulation efficacy, swelling index, loading capacity and in vitro release. The yields were varies from 78-101.99% and encapsulation efficacy varie from 81.10 to 81.6 % which encourage the investigation depends upon the combination of sodium alginate with various polymers. The various parameters of model equation of beads containing Metformin Hcl in vitro kinetic release were thoroughly investigated and it was seen that the statistically significant confined to Zero-order, Higuchi and Korsmeyer-Peppas model. To establish the release kinetic, Korsmeyer-Peppas model shows the prominent release characteristics. |
| Keywords: | Key Words: HPMC, Carbopol, Pectin and Sodium carboxy methyl cellulose. |
| Cite Article: | "A Review on Preparation and Evaluation of Sodium Alginate Beads with Metformin", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 1, page no.d256-d259, January-2024, Available :http://www.ijnrd.org/papers/IJNRD2401335.pdf |
| Downloads: | 000118764 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2401335 Registration ID: 213277 Published In: Volume 9 Issue 1, January-2024 DOI (Digital Object Identifier): Page No: d256-d259 Country: HYDERABAD, TELANGANA, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2401335 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2401335 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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