Paper Title
A Review on Preparation and Evaluation of Sodium Alginate Beads with Metformin
Article Identifiers
Authors
E. Bunny Priya
Keywords
Key Words: HPMC, Carbopol, Pectin and Sodium carboxy methyl cellulose.
Abstract
This present study an attempt was made to formulate beads of Metformin Hcl by using Sodium alginate in combination of HPMC , Carbopol ,Pectin and sodium carboxy methyl cellulose. Beads of metformin Hcl were successfully prepared by Ionotropic Gelation Method .The prepared beads evaluated for various parameters lke encapsulation efficacy, swelling index, loading capacity and in vitro release. The yields were varies from 78-101.99% and encapsulation efficacy varie from 81.10 to 81.6 % which encourage the investigation depends upon the combination of sodium alginate with various polymers. The various parameters of model equation of beads containing Metformin Hcl in vitro kinetic release were thoroughly investigated and it was seen that the statistically significant confined to Zero-order, Higuchi and Korsmeyer-Peppas model. To establish the release kinetic, Korsmeyer-Peppas model shows the prominent release characteristics.
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How To Cite (APA)
E. Bunny Priya (January-2024). A Review on Preparation and Evaluation of Sodium Alginate Beads with Metformin. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(1), d256-d259. https://ijnrd.org/papers/IJNRD2401335.pdf
Issue
Volume 9 Issue 1, January-2024
Pages : d256-d259
Other Publication Details
Paper Reg. ID: IJNRD_213277
Published Paper Id: IJNRD2401335
Downloads: 000121998
Research Area: Pharmacy
Country: HYDERABAD, TELANGANA, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2401335.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2401335
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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