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IJNRD
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

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Impact Factor : 8.76

Issue per Year : 12

Volume Published : 9

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Paper Title: FORMULATION, DEVELOPMENT AND EVALUATION OF FAST DESSOLVING TABLET OF LOSARTAN POTASSIUM AND NIFEDIPINE
Authors Name: SONALI PATIDAR , Shweta Sitole
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IJNRD_212606
Published Paper Id: IJNRD2401322
Published In: Volume 9 Issue 1, January-2024
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Abstract: Fast dissolving tablet format designed to allow administration of an oral dose form in the absence of water or fluid intake. The tablets rapidly dissolve or disintegrate in the saliva. Formulation research is oriented towards increasing the efficacy of existing drug molecule thought novel concepts of drug delivery. Losartan potassium and Nifedipine widely used as an antihypertensive drug. The aim of this study was to improve the solubility of Losartan potassium and nifedipine and increasing its disintegration time by formulation of fast dissolving tablets by direct compression method and various ratios of cross povidone (CP) cross carmellose sodium (CCS) sodium starch glycolate (SSG) as Superdisintegrants. The tablet pre compression parameter e.g. angle of repose, bulk density, tapped density, carr’s compressibility index and hausner’s ratio and post compression parameter like drug content uniformity, hardness, wetting time, friability, thickness, disintegration time, were evaluated for each formulation and found satisfactory.
Keywords: Losartan potassium, nifedipine, super disintegrants, fast dissolving tablets (FDTS).
Cite Article: "FORMULATION, DEVELOPMENT AND EVALUATION OF FAST DESSOLVING TABLET OF LOSARTAN POTASSIUM AND NIFEDIPINE", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 1, page no.d157-d166, January-2024, Available :http://www.ijnrd.org/papers/IJNRD2401322.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2401322
Registration ID: 212606
Published In: Volume 9 Issue 1, January-2024
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Page No: d157-d166
Country: KHARGONE, MP, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2401322
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2401322
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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