SUBSTITUTED-TRIAZOLES AND THEIR SCHIFF BASES AS ANTI-MICROBIAL AGENTS: A GENERAL REVIEW

SUBSTITUTED-TRIAZOLES AND THEIR SCHIFF BASES AS ANTI-MICROBIAL AGENTS: A GENERAL REVIEW

Registration ID: IJNRD_212514

Published ID: IJNRD2401148

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Namra M Shaikh , Dr. Channamma G M , Dr.Kishore Singh C.

1,2,4-Triazole. Biological activity. Schiff Base.

The global spread of drug resistance in bacteria requires new potent and safe antimicrobial agents. The Triazole derivatives possess divers biological activities such as antibacterial, antifungal, antiviral, anti-tubercular, anti-inflammatory, analgesic, antitumor, anticonvulsant and some other biological as well as chemical useful compounds. The biological profile of triazole moiety has attracted the attention of many researchers to explore its multiple potential against several biological activities. Compounds containing the 1, 2, 3-Triazole and 1, 2, 4-Triazole derivatives have acquired conspicuous significance due to their wide spectrum of biological activities. Triazole and its derivatives possess a great importance in medicinal chemistry and can be used for the synthesis of various compounds with different types of biological activities. A large volume of research on triazole and their derivatives has been carried out, proving significant antibacterial activity of this heterocyclic core. There is a growing demand for the preparation of new antimicrobial agents due to the developing resistance towards conventional antibiotics. The 1,2,3- triazole moiety does not occur in nature, although the synthetic molecules that contain 1,2,3-triazole units show diverse biological activities. This article covers the information of some triazoles derivatives having antimicrobial activities. Thus, triazole acts as a promising medicinal agent and can be helpful to develop new triazole compounds that could have better efficacy and lesser toxicity.

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"SUBSTITUTED-TRIAZOLES AND THEIR SCHIFF BASES AS ANTI-MICROBIAL AGENTS: A GENERAL REVIEW ", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 1, page no.b441-b450, January-2024, Available :https://ijnrd.org/papers/IJNRD2401148.pdf

Volume 9 Issue 1, January-2024

Pages : b441-b450

Paper Reg. ID: IJNRD_212514

Published Paper Id: IJNRD2401148

Downloads: 000121135

Research Area: Pharmacy

Country: KALABURGI, Karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2401148.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2401148

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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