Paper Title
"Transfersomes: Pioneering Nanovesicles in Enhanced Drug Delivery Systems"
Article Identifiers
: Keywords
Transfersomes, Transdermal drug delivery, Characterization, vesicular system, elastic vesicles, the transport mechanism.
Abstract
It is challenging to administer medications topically or transdermally, due to the fact that the skin serves as a barrier of protection. Most of the time, transdermal administering drugs is restricted by the skin's barrier function. The transdermal approach is regarded as the safest and most efficient because to its many benefits, which include identifiable and prolonged period for action, avoiding the first-pass metabolism, fewer side effects, etc. It also has several drawbacks, such as the inability to transport bigger molecules (>500D) and the inability to cross the stratum corneum barrier. Transfersomes was developed as an alternative to all of these issues because they had the advantages over other transdermal drug delivery systems and also had the ability to easily penetrate the barrier. They are novel vesicular drug delivery system for better transdermal absorption consisting of phospholipid, surfactant, and water. They include a high percentage of drug entrapment because to the natural phospholipids that build them up, and they are biocompatible and biodegradable. Using transfersomes, drugs that have low as well as high molecular weights can be transdermally administered. Transfersomes can deform and squeeze through extremely tiny openings since they are elastic by nature. The composition, preparation, and properties of transfersomes are discussed in detail in this review.
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How To Cite (APA)
P.MADHURI & K.SUPRIYA (January-2024). "Transfersomes: Pioneering Nanovesicles in Enhanced Drug Delivery Systems". INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(1), a346-a352. https://ijnrd.org/papers/IJNRD2401040.pdf
Issue
Volume 9 Issue 1, January-2024
Pages : a346-a352
Other Publication Details
Paper Reg. ID: IJNRD_212070
Published Paper Id: IJNRD2401040
Downloads: 000121995
Research Area: Pharmacy
Author Type: Indian Author
Country: BAPATLA, ANDHRA PRADESH , India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2401040.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2401040
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