INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
It is challenging to administer medications topically or transdermally, due to the fact that the skin serves as a barrier of protection. Most of the time, transdermal administering drugs is restricted by the skin's barrier function. The transdermal approach is regarded as the safest and most efficient because to its many benefits, which include identifiable and prolonged period for action, avoiding the first-pass metabolism, fewer side effects, etc. It also has several drawbacks, such as the inability to transport bigger molecules (>500D) and the inability to cross the stratum corneum barrier. Transfersomes was developed as an alternative to all of these issues because they had the advantages over other transdermal drug delivery systems and also had the ability to easily penetrate the barrier. They are novel vesicular drug delivery system for better transdermal absorption consisting of phospholipid, surfactant, and water. They include a high percentage of drug entrapment because to the natural phospholipids that build them up, and they are biocompatible and biodegradable. Using transfersomes, drugs that have low as well as high molecular weights can be transdermally administered. Transfersomes can deform and squeeze through extremely tiny openings since they are elastic by nature. The composition, preparation, and properties of transfersomes are discussed in detail in this review.
Keywords:
Transfersomes, Transdermal drug delivery, Characterization, vesicular system, elastic vesicles, the transport mechanism.
Cite Article:
""Transfersomes: Pioneering Nanovesicles in Enhanced Drug Delivery Systems"", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 1, page no.a346-a352, January-2024, Available :http://www.ijnrd.org/papers/IJNRD2401040.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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