Paper Title
SYNTHESIS, CHARACTERISATION, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF NOVEL BENZOTHIAZOLE DERIVATIVES
Article Identifiers
Authors
Sandhya M , Swaroopa H M , Manoj A Sharon , Nagesh T , Shahabas
Keywords
Benzothiazole, Antibacterial activity, anthelmintic activity.
Abstract
A design and synthesis of new Benzothiazole derivatives(3a-3h) containing thiazole moiety have been synthesized by conventional method by three step process by cyclization to form 2-amino benzothiazole, followed by Schiff’s bases mechanism and electrophilic substitution reaction with benzyl chloride. The synthesized compounds are characterized by 1H-NMR, IR and Mass spectral data. The synthesized compounds are evaluated for invitro antibacterial activity and anthelmintic activity against the antibacterial strains like gram-positive Bacillus substillus, Staphylococcus aureus gram-negative Escherichia coli, Klebsiella pneumoniae species and anthelmintic strains like Earthworms. The Streptomycin is considering as a reference standard drug for Anti- bacterial activity and Albendazole is considering as a reference standard drug for Anthelmintic activity. The compounds 3b, 3e and 3f showed good anti-bacterial activity and the compounds 3a, 3b and 3d showed good anthelmintic activity.
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How To Cite (APA)
Sandhya M, Swaroopa H M, Manoj A Sharon , Nagesh T, & Shahabas (December-2023). SYNTHESIS, CHARACTERISATION, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF NOVEL BENZOTHIAZOLE DERIVATIVES . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(12), d1-d16. https://ijnrd.org/papers/IJNRD2312301.pdf
Issue
Volume 8 Issue 12, December-2023
Pages : d1-d16
Other Publication Details
Paper Reg. ID: IJNRD_210312
Published Paper Id: IJNRD2312301
Downloads: 000121979
Research Area: Pharmacy
Country: Mandya, Karnataka , India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2312301.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2312301
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
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