Paper Title
Floting Drugs Delivery System
Article Identifiers
Authors
Kasar Utkarsh Balasaheb , Ghugarkar Prasad Gorakshnath , Kandekar Yash Rajendra , Kandekar Mahesh Raghunath , Sonawane Vivek Rajaram
Keywords
Gastro retentive system, Floating drug delivery system, Classification, Mechanism, Methods, Evaluation.
Abstract
Scientific and technological developments in the research and development of new drug delivery systems have been made in recent years by resolving physiological disorders, such as short gastric residence periods and unpredictable gastric emptying times. Dosage forms that can be hold within the stomach are called as Gastro-retentive Dosage Forms (GRDF). Multiple methods used in the prolongation of gastric residence time are floating drug delivery system, swelling and expanding system, polymeric bio-adhesive system, high density system and other delayed gastric emptying system. Medication-based disease treatment is entering a new era in which a increasing range of innovative drug delivery technologies are being used and are available for clinical use. Floating Drug Delivery Systems (FDDS) is one of the gastro-retentive dosage forms used to achieve extended duration of gastric residency. The aim of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with particular focus on the main floating mechanism to achieve gastric retention. Sustained oral release of gastrointestinal dosage types provides many benefits for drugs with absorption from the upper sections of the gastrointestinal tract and those that function locally throughout the stomach. This review includes the physiology, factors controlling gastric retention time, excipient variables influencing gastric retention, approaches to designing single-unit, hydro-dynamically balanced system and multi-unit floating structure, and aspects of their classification, formulation and evaluation are discussed in detail, and few applications of these systems.
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How To Cite (APA)
Kasar Utkarsh Balasaheb , Ghugarkar Prasad Gorakshnath , Kandekar Yash Rajendra , Kandekar Mahesh Raghunath , & Sonawane Vivek Rajaram (December-2023). Floting Drugs Delivery System . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(12), b714-b723. https://ijnrd.org/papers/IJNRD2312189.pdf
Issue
Volume 8 Issue 12, December-2023
Pages : b714-b723
Other Publication Details
Paper Reg. ID: IJNRD_210915
Published Paper Id: IJNRD2312189
Downloads: 000121977
Research Area: Pharmacy
Country: Ahmednagar , Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2312189.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2312189
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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