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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Floting Drugs Delivery System |
| Authors Name: | Kasar Utkarsh Balasaheb , Ghugarkar Prasad Gorakshnath , Kandekar Yash Rajendra , Kandekar Mahesh Raghunath , Sonawane Vivek Rajaram |
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| Author Reg. ID: |
IJNRD_210915
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| Published Paper Id: | IJNRD2312189 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | Scientific and technological developments in the research and development of new drug delivery systems have been made in recent years by resolving physiological disorders, such as short gastric residence periods and unpredictable gastric emptying times. Dosage forms that can be hold within the stomach are called as Gastro-retentive Dosage Forms (GRDF). Multiple methods used in the prolongation of gastric residence time are floating drug delivery system, swelling and expanding system, polymeric bio-adhesive system, high density system and other delayed gastric emptying system. Medication-based disease treatment is entering a new era in which a increasing range of innovative drug delivery technologies are being used and are available for clinical use. Floating Drug Delivery Systems (FDDS) is one of the gastro-retentive dosage forms used to achieve extended duration of gastric residency. The aim of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with particular focus on the main floating mechanism to achieve gastric retention. Sustained oral release of gastrointestinal dosage types provides many benefits for drugs with absorption from the upper sections of the gastrointestinal tract and those that function locally throughout the stomach. This review includes the physiology, factors controlling gastric retention time, excipient variables influencing gastric retention, approaches to designing single-unit, hydro-dynamically balanced system and multi-unit floating structure, and aspects of their classification, formulation and evaluation are discussed in detail, and few applications of these systems. |
| Keywords: | Gastro retentive system, Floating drug delivery system, Classification, Mechanism, Methods, Evaluation. |
| Cite Article: | "Floting Drugs Delivery System ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 12, page no.b714-b723, December-2023, Available :http://www.ijnrd.org/papers/IJNRD2312189.pdf |
| Downloads: | 000118762 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2312189 Registration ID: 210915 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: b714-b723 Country: Ahmednagar , Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2312189 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2312189 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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