PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL EVALUATION OF PLUCHEA LANCEOLATA LEAVES

Registration ID: IJNRD_210361

Published ID: IJNRD2312042

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Puja Ramu Basule , Zoya Fatema Sheikh , Pranali Arya , Pragati Zodape , Aslam Riyaz

Pluchea lanceolata, Extraction, Antioxidant activity, TLC, Screening method, Antibacterial activity.

Historically, medicinal plants have been the mainstay of human disease therapy. In the past, traditional systems of medicine have used the Asteraceae family member pluchea lanceolata (Rasna) as a bitter, laxative, and nervine tonic. The leaves of the plant, which are a part of the pluchea lanceolata species, are the focus of the current study's attention. It examines their pharmacological activity, pharmacognostic profile, and preliminary phytochemical research. Using a variety of criteria, such as ash value, extractive value, moisture content, etc., we investigated the antibacterial and antioxidant activity. P. lanceolata leaf extracts were used to investigate the in vitro antibiotic efficacy of four microorganisms. Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, and Bacillus subtilis at a temperature of 37 °C, these bacteria were cultivated in nutrient broth, Mueller Hinton agar and the Cup-Plate method were used to conduct an anti-microbial assay. A 400 ug/ml concentration of P. lanceolata extract and a 200 ug/ml concentration of the common antibiotic Amoxicillin were dissolved in DMSO solvent. The second activity, antioxidant activity, was evaluated spectrophotometrically by the DDPH (2, 2-Diphenyl-1-picrylhydrazyl) assay using ascorbic acid as a reference. Concentrations ranging from 100 to 500 g/ml of P. lanceolata leaf extracts in petroleum ether, ethyl acetate, and alcohol were created. According to the findings of the current investigation, pluchea lanceolata is an important source of many therapeutically useful components. Researchers have identified a variety of therapeutic characteristics for the plant after doing significant pharmacological research on it.

Published Paper   E-Certificate

Puja Ramu Basule , Zoya Fatema Sheikh , Pranali Arya , Pragati Zodape , & Aslam Riyaz (January-2024). PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL EVALUATION OF PLUCHEA LANCEOLATA LEAVES . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(1), a323-a335. https://ijnrd.org/papers/IJNRD2312042.pdf

Volume 9 Issue 1, January-2024

Pages : a323-a335

Paper Reg. ID: IJNRD_210361

Published Paper Id: IJNRD2312042

Downloads: 000121994

Research Area: Pharmacy

Country: Nagpur, MAHARASHTRA, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2312042.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2312042

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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