An overview: preparation of emulgel by using mefenamic acid

Registration ID: IJNRD_210294

Published ID: IJNRD2312040

DOI: Click Here to Get

Shaikh saba abdul ahad , Deepak joshi , Shamlila bawge , Shinde Madhuri

Emulgel, tropical drug delivery, hydrophobic drug, Mefenamic acid, emulsifying agent,

Emulgel are currently topic of attention to pharmaceutical scientists due to their high potential to act as drug delivery vehicle by incorporating high range of drug molecules. Emulgel due to lack of insoluble excipients and excessive oily bases it demonstrate better drug release as compared to other topical drug delivery system. The combined form of gel and emulsion referred as emulgel. Emulgel is promising drug delivery system of hydrophobic drugs it had dual release control system that is gel and emulsion. It is highly selective due to greaseless, easily removable, emollient and transparency also used got delivery of analgesic Antiinflammatory, antifungal, antiacne and various cosmetic formulation. Mefenamic acid 2-[(2,3-dimethylphenyl)amino]benzoic acid, it is a non-steroidal anti-inflammatory agent . Due to Oral administration this drug may produce severe gastrointestinal side effects like-ulceration and gastro intestinal bleeding. To overcome this of this problem lies in the fact that, topically applied NSAIDs are safer than oral NSAIDs.The purpose of the study is to prepare an emulgel of Mefenamic Acid using different gelling agents. After preparation of emulsion it get incorporated in different gelling agents like Carbopol 940, Carbopol 934, Lutrol 127 and Lutrol 87. After completion it's formulation evaluation of Mefenamic Acid emulgel carried out for Physical appearance, Spreadability, Extrudability, Rheological studies, Drug content and in vitro release, ph. [1, 3,23]

Published Paper   E-Certificate

Shaikh saba abdul ahad, Deepak joshi, Shamlila bawge, & Shinde Madhuri (December-2023). An overview: preparation of emulgel by using mefenamic acid. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(12), a308-a318. https://ijnrd.org/papers/IJNRD2312040.pdf

Volume 8 Issue 12, December-2023

Pages : a308-a318

Paper Reg. ID: IJNRD_210294

Published Paper Id: IJNRD2312040

Downloads: 000121979

Research Area: Pharmacy

Country: Latur, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2312040.pdf

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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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