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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ATORVASTATIN AND ASPIRIN IN API AND MARKETED FORMULATION BY USING U.V-VISIBLE SPECTROSCOPY |
| Authors Name: | D Snigdha , Tanzila Ayesha , Rumana Samreen , G Sanjeev , K Komala |
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IJNRD_208738
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| Published Paper Id: | IJNRD2311329 |
| Published In: | Volume 8 Issue 11, November-2023 |
| DOI: | |
| Abstract: | A specific, rapid and simple UV-Visible Spectrophotometric method with good sensitivity was developed and validated for the simultaneous estimation of atorvastatin and aspirin in standard solutions and tablets. The method employed solving of simultaneous equations based on the measurement of absorbance of two wavelengths, 295nm and 294nm for Atorvastatin and Aspirin, respectively. The calibration was linear for both the drugs in a concentration range of 10 to 80µg/ml and correlation coefficient provide the desired information on linearity. The results of analysis were validated statistically that included parameters such as Precision, LOD, LOQ, Recovery, Robustness & results were found in the acceptance criteria. It can be concluded from the results that present method for the simultaneous determination of atorvastatin and aspirin in tablets is specific, accurate, rapid and precise. |
| Keywords: | UV-Visible Spectrophotometric method, Atorvastatin, Aspirin, validatiоn, Limit of Detection, Limit of Quantification |
| Cite Article: | "ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ATORVASTATIN AND ASPIRIN IN API AND MARKETED FORMULATION BY USING U.V-VISIBLE SPECTROSCOPY", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 11, page no.d296-d309, November-2023, Available :http://www.ijnrd.org/papers/IJNRD2311329.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2311329 Registration ID: 208738 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): Page No: d296-d309 Country: Hanumakonda, Telangana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2311329 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2311329 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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