Paper Title
ANTI EPILEPTIC BIOACTIVE FACTORS IN A MEDICINAL PLANT CENTELLA ASIATICA
Article Identifiers
Authors
Dr. KANCHI SIVA PRASAD
Keywords
Key words: Centella asiatica, Epilepsy, Pentylenetetrazole, Triterpenoids.
Abstract
Abstract: This study mainly aimed at to investigate the antiepileptic property of a medicinal plant Centella asiatica against the Pentylenetetrazole (PTZ) induced epilepsy. Epilepsy is a convulsive episode and is the most frequent neurodegenerative disorder affecting about 50 million people world-wide. The epileptogenesis is a dynamic process with a tendency to develop hyperexcitability in one or other regions of the central nervous system. Epilepsy is not normally life-threatening, although physical injury can occur as a result of seizures. In rare cases, epilepsy can cause sudden, unexplained death. The primary treatment for epilepsy is the use of antiseizure medicines called anticonvulsant or antiepileptic drugs (AED) to bring seizures under control. Though considerable work has emerged during past several years from other countries, much is awaited from developing countries which are endowed with rich heritage of flora and fauna. It is in this context, efforts have been made in the present study to the neuropharmacological action of Centella asiatica with particular reference to anticonvulsant and neuroprotective activity. Centella asiatica is referred to as one of the great multipurpose miracle herbs of oriental medicine. It is considered as one of the most powerful rejuvenating herbs in Indian Ayurvedic medicine. The active constituents of Centella include triterpenoid glycosides i.e. asiatic acid, asiaticoside, madecassic acid, madecassoside, oxyasiaticoside, and centelloside. Saponin glycosides i.e. brahmiside, brahminoside. Flavonol glycosides i.e. quercetin-3-glycoside and Kampferol-3-glycoside and elements Calcium, Magnesium and Sodium.
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How To Cite (APA)
Dr. KANCHI SIVA PRASAD (November-2023). ANTI EPILEPTIC BIOACTIVE FACTORS IN A MEDICINAL PLANT CENTELLA ASIATICA. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(11), d218-d228. https://ijnrd.org/papers/IJNRD2311320.pdf
Issue
Volume 8 Issue 11, November-2023
Pages : d218-d228
Other Publication Details
Paper Reg. ID: IJNRD_209782
Published Paper Id: IJNRD2311320
Downloads: 000122005
Research Area: Life SciencesÂ
Country: GUDUR/ TIRUPATI DIST., ANDHRA PRADESH, INDIA
Published Paper PDF: https://ijnrd.org/papers/IJNRD2311320.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2311320
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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