Paper Title
Production of lovastatin by Aspergillus fischeri NCIM-509
Article Identifiers
Authors
Dr.D.Prasanna Latha , Prof.K.P.J.Hemalatha
Keywords
Lovastatin,Aspergillus fischeri,horse gram,grape pomace,sweet potato,solid state fermentation,process parameters,optimization
Abstract
Production of lovastatin was carried out by Aspergillus fischeri NCIM-509 using agro-industrial residue horse gram as substrate under solid state fermentation.Lovastatin is a potent hypercholesterolemic drug used for lowering blood cholesterol. In recent years,lovastatin has also been reported as a potential therapeutic agent for the treatment of various types of tumors and also play a tremendous role in the regulation of the inflammatory and immune response,coagulation process,bone marrow,neovascularization,vascular tone and arterial pressure.Process parameters like incubation time,temperature,moisture content,inoculum age,inoculum volume,pH of the medium,carbon source,lactose and nitrogen source were optimized and gave an overall yield of 13.5mg/gds of lovastatin after optimization.
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How To Cite (APA)
Dr.D.Prasanna Latha & Prof.K.P.J.Hemalatha (November-2023). Production of lovastatin by Aspergillus fischeri NCIM-509. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(11), b584-b594. https://ijnrd.org/papers/IJNRD2311172.pdf
Issue
Volume 8 Issue 11, November-2023
Pages : b584-b594
Other Publication Details
Paper Reg. ID: IJNRD_208496
Published Paper Id: IJNRD2311172
Downloads: 000121974
Research Area: Science & Technology
Country: Visakhapatnam, Andhra Pradesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2311172.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2311172
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