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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Development And Application Of Nanogels In Drug Delivery |
| Authors Name: | Nikhil Mahadev Kause , Dr. Prasad G. Ghugarkar |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_208745
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| Published Paper Id: | IJNRD2311147 |
| Published In: | Volume 8 Issue 11, November-2023 |
| DOI: | |
| Abstract: | Nanogels are produced through the dispersion of hydrogel using both physical and chemical cross-linking polymers on a nanoscale. These nanogels exhibit a distinctive blend of solid and liquid properties. It is postulated that prolonged contact between nanoparticles and the skin, when trapped within a nanogel, enhances the effectiveness of treatment. This review is based on the techniques for preparing, assessing, applications, advantages, and limitations of nanogel formulations as discussed in articles from reputable sources such as Scopus, PubMed, Medline, Google Scholar, and others. Various methods, including Emulsion Solvent Diffusion, Nano-precipitation, Emulsion Solvent Evaporation, Reverse Micellar, and Modified Emulsification-Diffusion, are employed to create nanogels. These nanogels undergo evaluation and characterization based on physical attributes, pH, spreadability, particle size distribution, homogeneity, drug content, FTIR, SEM, viscosity, in-vitro drug release, and stability. Importantly, they exhibit no creaming, flocculation, coalescence, or sedimentation, which are inherent issues in the manufacturing process. Nanogels are classified into five major types based on their responsiveness to stimuli. Notably, smaller particle sizes offer larger surface areas, resulting in increased activity. This makes nanogels valuable for enhancing the efficacy and potency of medicines. In summary, nanogels represent an efficient pathway for drug delivery with targeted precision. They hold significant promise in the field of pharmaceutical drug design and development, as they can reduce adverse effects and toxicity by limiting their impact on adjacent organs. |
| Keywords: | Nanogel, Preparation, Evaluation, Advantages, Applications |
| Cite Article: | "Development And Application Of Nanogels In Drug Delivery", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 11, page no.b359-b366, November-2023, Available :http://www.ijnrd.org/papers/IJNRD2311147.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2311147 Registration ID: 208745 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): Page No: b359-b366 Country: Ahmednagar, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2311147 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2311147 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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