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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | TO STUDY THE ANTIFUNGAL ACTIVITY OF ISAVUCONAZOLE |
| Authors Name: | Kranti Dipak Payghan , Miss.Kale Ishwari , Miss. Gunjawate Isha , Miss kolpe priti , Miss Jawale Jyoti |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_207797
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| Published Paper Id: | IJNRD2311036 |
| Published In: | Volume 8 Issue 11, November-2023 |
| DOI: | |
| Abstract: | A novel broad-spectrum triazole that is effective against molds, yeasts, and dimorphic fungi is called isavuconazole. In vitro, isavuconazole exhibits efficacy against the majority of medically significant fungus, such as species of Aspergillus, Candida, and Cryptococcus. This triazole has several benefits, such as an IV water-soluble formulation (which does not include cyclodextrin), good oral dosage form bioavailability, and consistent human pharmacokinetics. The US Food and Drug Administration has approved isavuconazole as a prodrug of isavuconazim, a more recent second-generation triazole antifungal. authorized for the management of invasive mucormycosis and aspergillosis. The activity spectrum of isavuconazole, is similar to the one of the polyene amphotericin B. However, because of these medications' inconsistent absorption, severe adverse effects, important drug interactions, and tendency toward bone resistance, their usage is frequently restricted. When treating invasive fungal infections, iavuconazole is a desirable alternative due to its outstanding pharmacokinetic qualities and safety.Their pharmacology, the field of chemistry, in vitro sensitivity, pharmacodynamics/pharmacokinetics, clinical efficacy, safety, tolerability, dosage, and administration are all summarized in this review. |
| Keywords: | Isavuconazole, Invasive fungal infections,Antifungal,Triazoles. |
| Cite Article: | "TO STUDY THE ANTIFUNGAL ACTIVITY OF ISAVUCONAZOLE ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 11, page no.a323-a334, November-2023, Available :http://www.ijnrd.org/papers/IJNRD2311036.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2311036 Registration ID: 207797 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): Page No: a323-a334 Country: -, -, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2311036 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2311036 |
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ISSN: 2456-4184
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