Paper Title

FORMULATION AND EVALUATION OF BILAYER ANTI DIABETIC TABLETS

Article Identifiers

Registration ID: IJNRD_207785

Published ID: IJNRD2310371

DOI: Click Here to Get

Authors

Sandesh Kumar , Yograj Mahajan , Vishal Gupta , Harish kumar Singh , Kumar Abhishek

Keywords

Glimeperide, Bilayer tablet, Xanthan gum, Magnesium Stearate Crospovidone, crosscarmellose sodium, microcrystalline cellulose

Abstract

Bilayer tablets of an Glimepiride hydrochloride is to formulate, and evaluate for oral sustained drug release, in pharmaceutical system to enhance its oral bioavailability, Reduction in drug toxicity, Reduction in dosing frequency of drug. Biphasic release is characterized by rapid initial release of the drug, followed by sustained rate of release. The drug released by the initial pulse, quickly attains the therapeutic plasma drug levels and ameliorates the slow onset of action of sustained release layer. This increases patient compliance as the patient is quickly relief. Such type of drug delivery systems is designed to deliver the drug in such a way that the drug level is maintained within the therapeutic window for a period as long as the system continues to deliver the drug and to avoid fluctuations in plasma drug level. The purpose of the research work was formulation development and evaluation bi-layer floating tablets of glimepiride to improve the oral therapeutic efficacy of these drugs exhibit pH dependent solubility and show good permeability from stomach and upper part of the small intestine into systemic circulation. Direct compression method form glimepiride was used to formulate bi-layer floating tablets.

How To Cite

"FORMULATION AND EVALUATION OF BILAYER ANTI DIABETIC TABLETS", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 10, page no.d522-d538, October-2023, Available :https://ijnrd.org/papers/IJNRD2310371.pdf

Issue

Volume 8 Issue 10, October-2023

Pages : d522-d538

Other Publication Details

Paper Reg. ID: IJNRD_207785

Published Paper Id: IJNRD2310371

Downloads: 000121163

Research Area: Engineering

Country: -, -, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2310371.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2310371

About Publisher

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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Call For Paper

Call For Paper - Volume 10 | Issue 8 | August 2025

IJNRD is Scholarly open access journals, Peer-reviewed, and Refereed Journals, High Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool), Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) with Open-Access Publications.

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

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Paper Submission Open For: August 2025

Current Issue: Volume 10 | Issue 8

Last Date for Paper Submission: Till 31-Aug-2025

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Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: International Peer-reviewed, Refereed, and Open Access Journal.

Subject Category: Research Area