INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Microspheres are typically free flow powders consisting of proteins or synthetic polymers which are biodegradable in nature. And ideally having a particle size less than 200μm. They are made from polymeric waxy or other protective materials such as natural, semi-synthetic and synthetic polymers. The therapeutic efficacy of microspheres contain drug depends upon their characteristics that can be altered in required terms by altering materials, methods, polymers, or techniques used. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumour. Microspheres are various types like Bio-adhesive microspheres, Magnetic microspheres, Floating microspheres, Radioactive microspheres, Polymeric microspheres, Biodegradable polymeric microspheres, Synthetic polymeric microspheres and are prepared by methods like Spray Drying, Solvent Evaporation, Single emulsion technique, Double emulsion technique, Phase separation coacervation technique, Spray drying and spray congealing, Solvent extraction, Quassi- emulsion solvent diffusion. The present review highlights various types of microspheres, different methods of preparation, its applications, and also various parameters to evaluate their efficiency.
Keywords:
Microsphere, Novel drug delivery, Tumor, Mucosal immunization, Spray dryer
Cite Article:
"Microsphere: A Comprehensive Review ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 10, page no.c760-c765, October-2023, Available :http://www.ijnrd.org/papers/IJNRD2310281.pdf
Downloads:
000118766
ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Facebook Twitter Instagram LinkedIn