DEVELOPMENT OF ANTIACNE HERBAL GEL

Registration ID: IJNRD_204943

Published ID: IJNRD2310088

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Ms. Kavita P. Saner, Dr. Avinsah V. Patil, Dr.Pravin N.Sable, Mrs. Rupali G. Chaudhari, Ms.Amruta U. Kamble

Acne vulgaris, eczema, fungicide, Cysts, spiky edges

Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous units, its prevalence is highest in adolescence, Where the individual encounters several psycho-social changes. Acne vulgaris affects over 80% of teenagers persists beyond the age of 25 years in 3% of men & 12% of women. Until now Synthetic medicines or antibiotics were used to treat acne. Herbal medications are considered safer than allopathic medicines. as these are Associated with side effects such as contact allergy, local irritation, scaling, itching, redness, Skin pilling etc. There are very few herbal antiacne. creams & gels available in the market & those are very costly. Keeping this mind our aim was to develop herbal anti-ache gel, to evaluate the physical characteristics of prepared formulations, to study effect on human volunteers. In this research work following activities was done. Preparation of material for the study. (i.e. selection of crude drugs, polymers, authentication, drying & storage of plants). Extraction of crude drugs by simple maceration process. Pharmacognostical study. Development of gel. Following plants were selected for development of antiacne formulation Aloe Vera is the word 'Aloe' comes from the Arabic word alloeh, which means ' a bitter, shiny substance.' This is an apt description for the dagger-shaped leaf, which has a bitter taste and spiky edges. Curcuma Longa is the Genus Name is derived from the Arab word 'kurkum'. Most likely it found its way to the Occident with the caravans of Arab traders. Its Sanskrit name is 'haridra', which means 'yellow wood'. Coriandrum Sativum is the name coriander comes from the Greek word koris, meaning "bug." It is likely named for the offensive bug-like smell coriander has when it is unripe Azadirachta Indica In India, neem is known as “the village pharmacy” because of its healing versatility, and it has been used in Ayurvedic medicine for more than 4,000 years due to its medicinal properties. Neem is also called ‘arista’ in Sanskrit- a word that means ‘perfect, complete and imperishable’. Ocimum sanctum- Known as "tulsi" or "Holy basil" is small Ocimum sanctum also commonly branched, & aromatic herb. It has height of about 70 cm. All the parts of have been widely used since thousands of years for various diseases & disorders with wide application in Ayurveda system of medicine. It has many properties like antioxidant, hepatoprotective, anti-inflammatory, antibacterial, antifungal with a wide margin of safety. Rubia cordifolia Rubia Cordifolia is a climbing herb, with red rhizomatous base & roots. It is an essential raw drug for the traditional herbal formulations. It is member of Rubiaceae family, the plant is commonly known as "Indian madder" and Sold under the trade name "manjistha". Rubia cordifolia extracts from the various parts of the plant are shown to have Several pharmacological benefits including ache & wound treatment.

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Ms. Kavita P. Saner, Dr. Avinsah V. Patil, Dr.Pravin N.Sable, Mrs. Rupali G. Chaudhari, & Ms.Amruta U. Kamble (October-2023). DEVELOPMENT OF ANTIACNE HERBAL GEL. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(10), a780-a792. https://ijnrd.org/papers/IJNRD2310088.pdf

Volume 8 Issue 10, October-2023

Pages : a780-a792

Paper Reg. ID: IJNRD_204943

Published Paper Id: IJNRD2310088

Research Area: Pharmacy

Author Type: Indian Author

Country: Pune, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2310088.pdf

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