INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
On the basis of various literature survey, triazole derivatives show various activity such as antibacterial, anti-inflammatory, antifungal, anticonvulsant, antitubercular, antioxidant, COX-2 inhibition, antimicrobial and anticancer activity. The possible improvements in the activity can be further achieved by slight modifications in the substituents on the basic triazole nucleus. As this moiety have remarkable biological activities which stimulated the research work in the field of heterocyclic chemistry. Hence it is intended for the synthesis, characterization and evaluation of biological activity of various types of derivatives belonging to the above classes of heterocyclic compounds. Prompted by the broad spectrum activities of triazole, series of 2-[(4-substituted)-5-mercapto-4H-1,2,4-triazol-3-yl]phenol (3a- 3f) and 3-[3-(2-hydroxyphenyl)-5-mercapto-4H-1,2,4-triazol-4-yl]-2-substituted thiazolidin-4-one (4a-4f) were designed and synthesized by reacting methyl salicylate with hydrazine hydrate. All these synthesize compounds were test for their antibacterial and anti-inflammatory activity.
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"Design and Synthesis of some Novel Heterocyclic Compounds of Triazoles of Biological Interest.", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 10, page no.a310-a322, October-2023, Available :http://www.ijnrd.org/papers/IJNRD2310037.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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