Paper Title
Advancements in Oro-dispersible Tablet Formulations: A Comprehensive Review of Novel Technologies and Emerging Trends
Article Identifiers
Authors
Rita Soyam , Keshav Hirave , Dnyaneshwar Mokaswad , Kamlesh Wadher , Millind Umekar
Keywords
Orodispersible, Pediatric, Regulatory Guidance, Dosage form.
Abstract
Orodispersible tablets (ODTs) have revolutionized pharmaceutical drug delivery by offering an innovative solution to challenges related to patient compliance, particularly in pediatric and geriatric populations. This review provides a comprehensive exploration of recent advancements in ODT formulations, encompassing novel technologies and emerging trends that have reshaped the landscape of oral medication administration. The review begins by delving into the intricate formulation strategies employed in ODT development, emphasizing the pivotal role of excipients, disintegration agents, and superdisintegrants in achieving rapid disintegration and dissolution. Innovative technologies such as freeze-drying, spray drying are highlighted for their potential in creating ODTs with improved mechanical strength, stability, and controlled drug release profiles. Furthermore, the integration of nanotechnology and nanomaterials is explored, showcasing their ability to provide precise control over drug release kinetics and bioavailability enhancement. Patient-centric design principles are woven throughout the review, emphasizing the need to tailor ODT formulations to meet the specific requirements of diverse patient populations. This includes considerations for geriatric patients with reduced saliva production and pediatric patients with unique dosing needs, ensuring safe and effective medication administration. The review also touches upon environmental sustainability in pharmaceutical manufacturing by examining the emergence of eco-friendly ODT materials and production processes. The utilization of biodegradable polymers and sustainable resources aligns with global efforts to reduce the ecological footprint of the pharmaceutical industry.
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How To Cite (APA)
Rita Soyam , Keshav Hirave, Dnyaneshwar Mokaswad, Kamlesh Wadher, & Millind Umekar (September-2023). Advancements in Oro-dispersible Tablet Formulations: A Comprehensive Review of Novel Technologies and Emerging Trends. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(9), b216-b234. https://ijnrd.org/papers/IJNRD2309124.pdf
Issue
Volume 8 Issue 9, September-2023
Pages : b216-b234
Other Publication Details
Paper Reg. ID: IJNRD_205215
Published Paper Id: IJNRD2309124
Downloads: 000121997
Research Area: Pharmacy
Country: Ahamadnagar, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2309124.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2309124
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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