Paper Title
The role of Withania somnifera in the Treatment of Hypertension : A Brief Review
Article Identifiers
Authors
Sakshi Angural
Keywords
Herb, Hypertension, Inflammation, Withanine, Vasodilation
Abstract
One of the important therapeutic plants in Indian systems of medicine is Withania somnifera, popularly known as ashwagandha. It has been utilised as a medication since the dawn of time, and is currently employed to treat a wide range of clinical ailments. The plant has a wide variety of various chemical ingredient classes, including flavonoids, steroidal lactones, and alkaloids. Different biological activities of the plant are carried out by these chemical moieties. A plant's anti-inflammatory, anticancer, neuroprotective, antibacterial, antistress, antidiabetic, and cardioprotective properties were proven in laboratory research. These medicinal effects are partly attributable to W. somnifera's capacity to lower reactive oxygen species, modify mitochondrial activity, control apoptosis, lower inflammation, and improve endothelial function. It has also been used alone or in combination to treat a number of human disorders. Hypertension, commonly known as high blood pressure, is a significant risk factor for cardiovascular diseases and other health complications. Pulmonary hypertension (PH) is a complex and progressive disorder characterized by increased blood pressure in the pulmonary arteries, leading to significant cardiovascular and respiratory complications. Despite advancements in therapeutic options, the management of PH remains challenging. Here, we review the pharmacological, ethnobotanical, and medicinal properties of the plant and its main chemical components.and explore the potential role of Withania somnifera in the treatment of pulmonary hypertension based on its pharmacological properties and relevant preclinical studies.
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How To Cite (APA)
Sakshi Angural (August-2023). The role of Withania somnifera in the Treatment of Hypertension : A Brief Review. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(8), d406-d412. https://ijnrd.org/papers/IJNRD2308360.pdf
Issue
Volume 8 Issue 8, August-2023
Pages : d406-d412
Other Publication Details
Paper Reg. ID: IJNRD_204407
Published Paper Id: IJNRD2308360
Downloads: 000121979
Research Area: Science
Country: Jammu, Jammu and Kashmir, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2308360.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308360
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