The role of Withania somnifera in the Treatment of Hypertension : A Brief Review

The role of Withania somnifera in the Treatment of Hypertension : A Brief Review

Registration ID: IJNRD_204407

Published ID: IJNRD2308360

DOI: Click Here to Get

Sakshi Angural

Herb, Hypertension, Inflammation, Withanine, Vasodilation

One of the important therapeutic plants in Indian systems of medicine is Withania somnifera, popularly known as ashwagandha. It has been utilised as a medication since the dawn of time, and is currently employed to treat a wide range of clinical ailments. The plant has a wide variety of various chemical ingredient classes, including flavonoids, steroidal lactones, and alkaloids. Different biological activities of the plant are carried out by these chemical moieties. A plant's anti-inflammatory, anticancer, neuroprotective, antibacterial, antistress, antidiabetic, and cardioprotective properties were proven in laboratory research. These medicinal effects are partly attributable to W. somnifera's capacity to lower reactive oxygen species, modify mitochondrial activity, control apoptosis, lower inflammation, and improve endothelial function. It has also been used alone or in combination to treat a number of human disorders. Hypertension, commonly known as high blood pressure, is a significant risk factor for cardiovascular diseases and other health complications. Pulmonary hypertension (PH) is a complex and progressive disorder characterized by increased blood pressure in the pulmonary arteries, leading to significant cardiovascular and respiratory complications. Despite advancements in therapeutic options, the management of PH remains challenging. Here, we review the pharmacological, ethnobotanical, and medicinal properties of the plant and its main chemical components.and explore the potential role of Withania somnifera in the treatment of pulmonary hypertension based on its pharmacological properties and relevant preclinical studies.

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"The role of Withania somnifera in the Treatment of Hypertension : A Brief Review", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 8, page no.d406-d412, August-2023, Available :https://ijnrd.org/papers/IJNRD2308360.pdf

Volume 8 Issue 8, August-2023

Pages : d406-d412

Paper Reg. ID: IJNRD_204407

Published Paper Id: IJNRD2308360

Downloads: 000121186

Research Area: Science

Country: Jammu, Jammu and Kashmir, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308360.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308360

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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