THE PROTECTIVE EFFECT OF CISPLATIN NEPHROTOXICITY IN MICE ON MELATONIN AND GLUTATHIONE

THE PROTECTIVE EFFECT OF CISPLATIN NEPHROTOXICITY IN MICE ON MELATONIN AND GLUTATHIONE

Registration ID: IJNRD_203994

Published ID: IJNRD2308323

DOI: Click Here to Get

AJAY KUMAR , NEERAJ KUMAR

Cisplatin nephrotoxicity lipid peroxidation antioxidant and Glutathione

Cisplatin Nephrotoxicity Several theories have been put forth, but one that stands out is oxidative stress (including glutathione depletion and lipid peroxide generation). This study explains how the antioxidant system contributes to the nephrotoxicity caused by cisplatin and the nephroprotection provided by melatonin. Albino mice (BALB/c) were intravenously injected with: 1) Vehicle management 2) a single 6.5 mg/kg dosage CP group for cisplatin: 3) Melatonin 10 mg/kg for five days following CP injection. CPM team: 4) five days of melatonin (10 mg/kg) before and after CP injection The MCPM group: 5) M group received 10 mg/kg of melatonin daily for 5 days. In order to measure serum creatinine and blood urea nitrogen (BUN) mice were slaughtered five days after receiving CP injections

Published Paper   E-Certificate

"THE PROTECTIVE EFFECT OF CISPLATIN NEPHROTOXICITY IN MICE ON MELATONIN AND GLUTATHIONE", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 8, page no.d44-d51, August-2023, Available :https://ijnrd.org/papers/IJNRD2308323.pdf

Volume 8 Issue 8, August-2023

Pages : d44-d51

Paper Reg. ID: IJNRD_203994

Published Paper Id: IJNRD2308323

Downloads: 000121128

Research Area: Pharmacy

Country: HAPUR, UTTAR PRADESH, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308323.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308323

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

Call For Paper - Volume 10 | Issue 8 | August 2025

IJNRD is Scholarly open access journals, Peer-reviewed, and Refereed Journals, High Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool), Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) with Open-Access Publications.

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

Indexing In Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar | AI-Powered Research Tool, Microsoft Academic, Academia.edu, arXiv.org, Research Gate, CiteSeerX, ResearcherID Thomson Reuters, Mendeley : reference manager, DocStoc, ISSUU, Scribd, and many more

How to submit the paper?

Important Dates for Current issue

Paper Submission Open For: August 2025

Current Issue: Volume 10 | Issue 8

Last Date for Paper Submission: Till 31-Aug-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: International Peer-reviewed, Refereed, and Open Access Journal.

Subject Category: Research Area