Paper Title

Superdisintegrants and Their Unavoidable Role in Oral Disintegrating Tablets

Article Identifiers

Registration ID: IJNRD_203483

Published ID: IJNRD2308232

DOI: Click Here to Get

Authors

Asmita Ghorpade , Suhas Siddheshwar , Someshwar Mankar

Keywords

Super-disintegrants, Dysphagia, Biocompatible, Biodegradable

Abstract

Oral disintegrating tablet are generally intended for the route via mouth cavity. The chief excipient used for oral disintegration tablet is superdisintegrant. Many superdisintegrants either natural and synthetic are used in pharmaceutical industry. Among this the natural superdisintegrants offer an additional advantage over the synthetic superdisntegrants. The mechanism of action of superdisintegrants is generally divided into seven basic types such as Capillary action, Swelling, Chemical reaction, Particle repulsive force, Deformation recovery, Enzymatic reaction and Combination reaction. The natural disintegrants such as Ispaghula (Plantago ovata seed mucilage), Lepidium sativum Seed Mucilage, Fenugreek seed mucilage and chitosan agar and starch are mostly used. Synthetic superdisintegrants such as crospovidone. cross carmellose sodium, sodium starch glycolate are commonly used in pharmaceutical industry for oral disintegrating tablets. Superdisintegrants have three basic addition process such as intragranular, extragranlar and partly internal and external depending upon the formulation and nature of API. This article includes all the details for natural and synthetic superdisintegrants.

How To Cite (APA)

Asmita Ghorpade, Suhas Siddheshwar, & Someshwar Mankar (August-2023). Superdisintegrants and Their Unavoidable Role in Oral Disintegrating Tablets. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(8), c223-c232. https://ijnrd.org/papers/IJNRD2308232.pdf

Issue

Volume 8 Issue 8, August-2023

Pages : c223-c232

Other Publication Details

Paper Reg. ID: IJNRD_203483

Published Paper Id: IJNRD2308232

Downloads: 000121979

Research Area: Pharmacy

Country: Ahmednagar, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308232.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308232

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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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Call For Paper - Volume 10 | Issue 10 | October 2025

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Current Issue: Volume 10 | Issue 10 | October 2025

Impact Factor: 8.76

Last Date for Paper Submission: Till 31-Oct-2025

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