INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Oral disintegrating tablet are generally intended for the route via mouth cavity. The chief excipient used for oral disintegration tablet is superdisintegrant. Many superdisintegrants either natural and synthetic are used in pharmaceutical industry. Among this the natural superdisintegrants offer an additional advantage over the synthetic superdisntegrants. The mechanism of action of superdisintegrants is generally divided into seven basic types such as Capillary action, Swelling, Chemical reaction, Particle repulsive force, Deformation recovery, Enzymatic reaction and Combination reaction. The natural disintegrants such as Ispaghula (Plantago ovata seed mucilage), Lepidium sativum Seed Mucilage, Fenugreek seed mucilage and chitosan agar and starch are mostly used. Synthetic superdisintegrants such as crospovidone. cross carmellose sodium, sodium starch glycolate are commonly used in pharmaceutical industry for oral disintegrating tablets. Superdisintegrants have three basic addition process such as intragranular, extragranlar and partly internal and external depending upon the formulation and nature of API. This article includes all the details for natural and synthetic superdisintegrants.
"Superdisintegrants and Their Unavoidable Role in Oral Disintegrating Tablets", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.c223-c232, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308232.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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