Superdisintegrants and Their Unavoidable Role in Oral Disintegrating Tablets

Superdisintegrants and Their Unavoidable Role in Oral Disintegrating Tablets

Registration ID: IJNRD_203483

Published ID: IJNRD2308232

DOI: Click Here to Get

Asmita Ghorpade , Suhas Siddheshwar , Someshwar Mankar

Super-disintegrants, Dysphagia, Biocompatible, Biodegradable

Oral disintegrating tablet are generally intended for the route via mouth cavity. The chief excipient used for oral disintegration tablet is superdisintegrant. Many superdisintegrants either natural and synthetic are used in pharmaceutical industry. Among this the natural superdisintegrants offer an additional advantage over the synthetic superdisntegrants. The mechanism of action of superdisintegrants is generally divided into seven basic types such as Capillary action, Swelling, Chemical reaction, Particle repulsive force, Deformation recovery, Enzymatic reaction and Combination reaction. The natural disintegrants such as Ispaghula (Plantago ovata seed mucilage), Lepidium sativum Seed Mucilage, Fenugreek seed mucilage and chitosan agar and starch are mostly used. Synthetic superdisintegrants such as crospovidone. cross carmellose sodium, sodium starch glycolate are commonly used in pharmaceutical industry for oral disintegrating tablets. Superdisintegrants have three basic addition process such as intragranular, extragranlar and partly internal and external depending upon the formulation and nature of API. This article includes all the details for natural and synthetic superdisintegrants.

Published Paper   E-Certificate

"Superdisintegrants and Their Unavoidable Role in Oral Disintegrating Tablets", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 8, page no.c223-c232, August-2023, Available :https://ijnrd.org/papers/IJNRD2308232.pdf

Volume 8 Issue 8, August-2023

Pages : c223-c232

Paper Reg. ID: IJNRD_203483

Published Paper Id: IJNRD2308232

Downloads: 000121180

Research Area: Pharmacy

Country: Ahmednagar, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308232.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308232

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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