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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | BIOCHEMICAL AND LARVICIDAL IMPACT OF APIGENIN AND RUTIN IN THEIR BINARY COMBINATION (1:2) AGAINST ELEPHANTIASIS VECTOR CULEX QUINQUEFASCIATUS |
| Authors Name: | Abhay Deep Johnson , Vikas Chandra Verma , Ajay Singh |
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IJNRD_203655
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| Published Paper Id: | IJNRD2308149 |
| Published In: | Volume 8 Issue 8, August-2023 |
| DOI: | |
| Abstract: | Phytochemicals are safe for non-target organisms like man and vector borne diseases due to insecticidal nature. Larvicidal activity of biologically active compounds i.e. Apigenin and Rutin extracted from the leaves of Jatropha gossypifolia and Codiaeum variegatum against larvae of Culex quinquefasciatus was studied in their binary combination (1:2). Standard WHO protocols was adopted for the larvicidal bioassay. The active compounds i.e. Apigenin and Rutin extracted through ethyl alcohol from the leaves of Euphorbious plants was administered for 24h, 48h, 72h and 96h to the larvae of C. quinquefasciatus. Exposure of larvae over 24h to 96h sub-lethal doses (40% and 80% of LC50) of Apigenin and Rutin in the ratio 1:2, significantly (P<0.05) altered the biochemical levels like total protein, total free amino acid, glycogen and activities of enzymes acetylcholinesterase, acid and alkaline phosphatases in whole body tissue of the larvae. The alteration in all these biochemical parameters were significantly(P<0.05) time and dose dependent. It may act as an ecofriendly measure to manage the population of filarial vector Culex quinquefasciatus. |
| Keywords: | Jatropha gossypifolia, Codiaeum variegatum, Apigenin, Rutin and Culex quinquefasciatus |
| Cite Article: | "BIOCHEMICAL AND LARVICIDAL IMPACT OF APIGENIN AND RUTIN IN THEIR BINARY COMBINATION (1:2) AGAINST ELEPHANTIASIS VECTOR CULEX QUINQUEFASCIATUS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.b391-b402, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308149.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2308149 Registration ID: 203655 Published In: Volume 8 Issue 8, August-2023 DOI (Digital Object Identifier): Page No: b391-b402 Country: -, -, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2308149 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2308149 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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