Seizures in term babies and neurodevelopmental outcome: a follow-up study

Registration ID: IJNRD_203504

Published ID: IJNRD2308123

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Prof M A Wahed

Key words: Term baby, convulsion, NICU admission, neurodevelopmental outcome.

Seizures in term babies and neurodevelopmental outcome: a follow-up study Prof. M A Wahed, Head of Child Health, Rangpur Mother and Children Hospital, Bangladesh. Abstract Introduction: Neonatal period is the most vulnerable time for the occurrence of seizures. There are various etiological factors of neonatal seizures and increasing evidence suggests that neonatal seizures are associated with adverse neurodevelopment outcomes. Objectives: The objectives were determination of causes of neonatal seizures with outcome during management and long-term post-natal outcome. Material & Methods: This was a prospective cross-sectional Hospital based study conducted in Rangpur Mother and Children Hospital from 1st July to 2017 to 30th June 2022. Term newborn babies admitted in Neonatal Intensive Care Unit with convulsion were the samples. A prepared and pretested “Protocol” containing Part-A and Part-B was used - Part-A in Neonatal Intensive Care Unit and Part-B in the attached Disability Research Center for periodic follow up. Standard guidelines were followed in clinical diagnosis, laboratory investigations and management of convulsion. The survivors were followed-up periodically. Simple statistical calculations were performed. Results: A total of 234 term neonates with convulsion were admitted from 1st July 2017 to 30th June 2018. Among them, 15 expired during treatment, 10 babies taken out on Risk Bond by parents and 212 children were discharged and referred to Disability Research Center for follow-up assessment. Follow-up was continued up to 30th June 2022 and 37 children were lost from regular follow-up. Finally, data from 175 children were analyzed. Among these 110 (62.9%) children were male and 65 (27.1%) were female. HIE stage-II was present in 133 (76.0%) samples and 20 (11.3%) had metabolic disturbances. Clonic convulsion was present in 114 (65.0%) samples and subtle convulsion in 45 (26.0%) samples. HIE was the potent predictor for developing neurodevelopmental sequelae. Conclusions: Neonatal seizures have different etiology. Among them HIE stage-II is the predominant cause of admission as well as adverse neurodevelopmental outcomes.

Published Paper   E-Certificate

Prof M A Wahed (August-2023). Seizures in term babies and neurodevelopmental outcome: a follow-up study. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(8), b184-b192. https://ijnrd.org/papers/IJNRD2308123.pdf

Volume 8 Issue 8, August-2023

Pages : b184-b192

Paper Reg. ID: IJNRD_203504

Published Paper Id: IJNRD2308123

Downloads: 000122001

Research Area: Medical Science

Author Type: Foreign Author

Country: Rangpur, Not applicale, Bangladesh

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308123.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308123

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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