Paper Title
EVALUATION OF ANTIDIABETIC ACTIVITY OF HYDROALCOHOLIC LEAVES EXTRACT OF RUMEX ALPINES PLANT
Article Identifiers
Authors
Miss Muskan Rathor , Mr. Narendra Patel , Dr. C.K. Tyagi , Dr. Sujata Kushwaha , Mr. Firoz Khan
Keywords
Rumex alpines leaves extract, Glibenclamide, 'Alloxan monohydrate
Abstract
The present study was designed to evaluate the antidiabetic potential of the hydroalcoholic extract of Rumex alpines leaves using in vivo approaches. For in vivo studies, blood glucose level was monitored at different intervals after administration of varying doses of the extract for its anti-hyperglycemic effect in normoglycemic and diabetic wistar rats. Hydroalcoholic leaves extract of Rumex alpines was screened for antidiabetic activity and given to the 'Alloxan monohydrate'-induced diabetic rats at a concentration of 250 mg/kg and 500 mg/kg of body weight in different groups of 6 diabetic rats each orally once a day for 15 days. Glibenclamide is given to another group to support the result at a dose of (600µg/kg p.o.) of body weight orally once a day for 15 days. The plant extract showed significant antihyperglycemic effect in normoglycemic and diabetic wistar rats. The results demonstrate that hydroalcoholic leaves extract of Rumex alpines possess antidiabetic property.
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How To Cite (APA)
Miss Muskan Rathor, Mr. Narendra Patel, Dr. C.K. Tyagi, Dr. Sujata Kushwaha, & Mr. Firoz Khan (July-2023). EVALUATION OF ANTIDIABETIC ACTIVITY OF HYDROALCOHOLIC LEAVES EXTRACT OF RUMEX ALPINES PLANT. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(7), e648-e657. https://ijnrd.org/papers/IJNRD2307479.pdf
Issue
Volume 8 Issue 7, July-2023
Pages : e648-e657
Other Publication Details
Paper Reg. ID: IJNRD_202882
Published Paper Id: IJNRD2307479
Downloads: 000121982
Research Area: Engineering
Country: -, -, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2307479.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2307479
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