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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | ROLE OF CYCLOSPORINE A (CsA) IN MANAGEMENT OF INTERSTITIAL LUNG DISEASES ASSOCIATED WITH RHEUMATOID ARTHRITIS (RA-ILD) |
| Authors Name: | Bandari Vamshipriya , A.srinivasa rao , A.V.kishore babu |
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IJNRD_202628
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| Published Paper Id: | IJNRD2307421 |
| Published In: | Volume 8 Issue 7, July-2023 |
| DOI: | |
| Abstract: | Interstitial lung disease associated with Rheumatoid Arthritis (RA- ILD) is due to pathology and complication of disease or due to prolonged use DMARDS or conventional drugs used for management of RA. Cyclosporine A is an immunosuppressive drug which inhibits the t-cell activation and decrease the ILD related reaction with high efficacy and minimal adverse effects. So cyclosporine is considered for prophylactic and therapeutic management of RA-ILD treatment. Cyclosporine A is effective drug for treatment of intestinal lung disease and its complications. It is more effective with combination with methotrexate and corticosteroids than monotherapy which has been proven in various previous literatures. So the cyclosporine is choice of drug for effective treatment of intestinal lung disease associated with rheumatoid arthritis to prevent further complications like airway and pleural diseases, respiratory infections etc.. Compare to conventional drugs used in management of rheumatoid arthritis cyclosporine A is better choice for prevention of complications like ILD, other lung infections and other systemic illness. It has major role in suppression of inflammatory reaction in Interstitial lung disease associated with Rheumatoid Arthritis. Upon combination its has higher efficacy rate than monotherapy .it has better therapeutic range and low risk profile but on over usage it lead to nephrotoxicity |
| Keywords: | “Rheumatoid arthritis” , “interstitial lung disease” , “cyclosporine A”, “methotrexate”, “corticosteroids”, conventional DMARDS” ‘ |
| Cite Article: | "ROLE OF CYCLOSPORINE A (CsA) IN MANAGEMENT OF INTERSTITIAL LUNG DISEASES ASSOCIATED WITH RHEUMATOID ARTHRITIS (RA-ILD)", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 7, page no.e178-e185, July-2023, Available :http://www.ijnrd.org/papers/IJNRD2307421.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2307421 Registration ID: 202628 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): Page No: e178-e185 Country: Hyderabad, Telangana, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2307421 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2307421 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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