ROLE OF CYCLOSPORINE A (CsA) IN MANAGEMENT OF INTERSTITIAL LUNG DISEASES ASSOCIATED WITH RHEUMATOID ARTHRITIS (RA-ILD)

Registration ID: IJNRD_202628

Published ID: IJNRD2307421

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Bandari Vamshipriya , A.srinivasa rao , A.V.kishore babu

“Rheumatoid arthritis” , “interstitial lung disease” , “cyclosporine A”, “methotrexate”, “corticosteroids”, conventional DMARDS” ‘

Interstitial lung disease associated with Rheumatoid Arthritis (RA- ILD) is due to pathology and complication of disease or due to prolonged use DMARDS or conventional drugs used for management of RA. Cyclosporine A is an immunosuppressive drug which inhibits the t-cell activation and decrease the ILD related reaction with high efficacy and minimal adverse effects. So cyclosporine is considered for prophylactic and therapeutic management of RA-ILD treatment. Cyclosporine A is effective drug for treatment of intestinal lung disease and its complications. It is more effective with combination with methotrexate and corticosteroids than monotherapy which has been proven in various previous literatures. So the cyclosporine is choice of drug for effective treatment of intestinal lung disease associated with rheumatoid arthritis to prevent further complications like airway and pleural diseases, respiratory infections etc.. Compare to conventional drugs used in management of rheumatoid arthritis cyclosporine A is better choice for prevention of complications like ILD, other lung infections and other systemic illness. It has major role in suppression of inflammatory reaction in Interstitial lung disease associated with Rheumatoid Arthritis. Upon combination its has higher efficacy rate than monotherapy .it has better therapeutic range and low risk profile but on over usage it lead to nephrotoxicity

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Bandari Vamshipriya , A.srinivasa rao , & A.V.kishore babu (July-2023). ROLE OF CYCLOSPORINE A (CsA) IN MANAGEMENT OF INTERSTITIAL LUNG DISEASES ASSOCIATED WITH RHEUMATOID ARTHRITIS (RA-ILD). INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(7), e178-e185. https://ijnrd.org/papers/IJNRD2307421.pdf

Volume 8 Issue 7, July-2023

Pages : e178-e185

Paper Reg. ID: IJNRD_202628

Published Paper Id: IJNRD2307421

Downloads: 000121991

Research Area: Medical Science

Author Type: Indian Author

Country: Hyderabad, Telangana, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2307421.pdf

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