|
|||||||||||||||
|
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
||||||||||||||
Issue: May 2024
Volume 9 | Issue 5
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.76
Issue per Year : 12
Volume Published : 9
Issue Published : 96
Article Submitted :
Article Published :
Total Authors :
Total Reviewer :
Total Countries :
Indexing Partner
Join RMS/Earn 300
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ANTIDIABETIC DRUGS (METFORMIN AND LINAGLIPTIN) IN TABLET DOSAGE FORM BY USING RP- HPLC METHOD |
| Authors Name: | Anjali Chouhan , Neelam Rathore , Anubhav Shrivastava , Mahendra Singh Tomar , Shubham Singh Panwar |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_202469
|
| Published Paper Id: | IJNRD2307416 |
| Published In: | Volume 8 Issue 7, July-2023 |
| DOI: | |
| Abstract: | A new, simple, precise, accurate and reproducible RP-HPLC method for Simultaneous estimation of bulk and pharmaceutical formulations. Separation of Metformin and Linagliptin was successfully achieve dona THERMO, C18, 250cmx4.6mm, 5µm or equivalent in an isocratic mode utilizing KH2PO4: Methanol (65:35) at a flow rate of 1.0mL/min and eluate was monitored at 226nm, with a retention time of 3.132 and 3.728 minutes for Metformin and Linagliptin respectively. The method was validated and found to be linear in the drug concentration range of 50µg/ml to150 µg/ml for Metformin and 50µg/ml to150 µg/ml for Linagliptin. The values of the correlation coefficient were found to 0.999for Metformin and 1 for Linagliptin respectively. The LOD and LOQ for Metformin were found to be 1.909 and 6.362 respectively. The LOD and LOQ for Linagliptin were found to be 0.0349 and 0.1163 respectively. This method was found to be good percentage recovery for Metformin and Linagliptin were found to be 100 and 100 respectively indicates that the proposed method is highly accurate. The method was extensively validated according to ICH guidelines for Linearity, Accuracy, Precision, Specificity and Robustness. |
| Keywords: | Metformin, Linagliptin, High performance liquid chromatography. |
| Cite Article: | "ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ANTIDIABETIC DRUGS (METFORMIN AND LINAGLIPTIN) IN TABLET DOSAGE FORM BY USING RP- HPLC METHOD", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 7, page no.e141-e150, July-2023, Available :http://www.ijnrd.org/papers/IJNRD2307416.pdf |
| Downloads: | 000118757 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID:IJNRD2307416 Registration ID: 202469 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): Page No: e141-e150 Country: ujjain, M. P., India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2307416 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2307416 |
| Share Article: |
|
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijnrd.org
| Semantic Scholar | Microsaoft Academic | ORCID | Zenodo |
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | PUBLON |
| DRJI | SSRN | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Social Media
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Join RMS/Earn 300
| Copyright © 2024 - All Rights Reserved - IJNRD |
Facebook Twitter Instagram LinkedIn