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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF TARTARIC ACID FROM EFFERVESCENT GRANULES BY RP-HPLC |
| Authors Name: | Dr. Ameya Mulay , Harshali Thakare , Sudhir Shinde , Mahendra Godase , Suhas Wale |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_202278
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| Published Paper Id: | IJNRD2307376 |
| Published In: | Volume 8 Issue 7, July-2023 |
| DOI: | http://doi.one/10.1729/Journal.35364 |
| Abstract: | The analytical method was developed and validated for Tartaric acid Effervescent formulation by using RP- HPLC. The appropriate meth-od optimized for the assay of Tartaric acid and validated as per ICH 2005 guidelines. For the analysis, 210 nm wavelength on UV/visible detector were selected, with the Mobile phase 0.01 M Potassium Dihydrogen Phosphate, pH 2.6. maintained with Orthophosphoric Acid. The chromatographic conditions for the best separation of Tartaric acid, RP-column C18 Shimadzu GIST Shim Pack (4.6 x 250 mm, 5 μm particle size) with a flow rate of 1.0 mL/ min, and injection volume of 20 µL. The oven is set to a temperature of around 30 °C. The method was validated for specificity, linearity, precision, accuracy, and robustness. The developed method was found to be linear and precision was evaluated by replicate analysis in which Relative Standard Deviation (RSD) values for areas were found below 2.0%. The recoveries ob-tained (100.83%–101.54%) ensured the accuracy of the developed method. Accordingly, the proposed developed and validated procedure was proved to be suitable for routine analysis of Tartaric acid. |
| Keywords: | HPLC, Tartaric Acid, Effervescent, Analytical Method Development |
| Cite Article: | "ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF TARTARIC ACID FROM EFFERVESCENT GRANULES BY RP-HPLC", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 7, page no.d662-d667, July-2023, Available :http://www.ijnrd.org/papers/IJNRD2307376.pdf |
| Downloads: | 000118761 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2307376 Registration ID: 202278 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.35364 Page No: d662-d667 Country: Mumbai, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2307376 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2307376 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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