Comparable Antimicrobial Activity Evaluation of Drumstick (Moringa oleifera Lam.) leaves extract against bacterial isolates

Comparable Antimicrobial Activity Evaluation of Drumstick (Moringa oleifera Lam.) leaves extract against bacterial isolates

Registration ID: IJNRD_201751

Published ID: IJNRD2307231

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ANSHU MALA , MANU VIVEK

Moringa, MIC value, leaf extracts, antimicrobial activity, bacterial strains

Drumstick, also known as Moringa oleifera Lam., is a wild and cultivated plant of the genus Moringa that belongs to the family Moringaceae. While having no negative side effects, its plant extracts have good therapeutic qualities that are comparable to antibiotics. In order to learn more about the antibacterial activity of Moringa extracts prepared in different solvents, including water, methanol, ethyl acetate, ethanol, and chloroform, the current investigation was undertaken utilising air dried fresh Moringa leaves. By keeping an eye on the Minimum Inhibitory Concentration (MIC) value, one can determine the antibacterial activity of Moringa leaf extracts made in these solvents. Different solvent-based extracts demonstrated antibiotic activity against a variety of pathogens, including Bacillus subtilis, Staphylococcus aureus and Escherichia coli. It was shown that leaf extracts in methanol and ethyl acetate were more efficient than those in ethanol. According to MIC values, Bacillus subtilis (23 mg/ml) was the bacterial strain that was most sensitive to moringa extract, followed by Staphylococcus aureus (25 mg/ml) and Escherichia coli (29 mg/ml). Staphylococcus aureus (15 mg/ml) was the strain that was most sensitive to the antibiotic tetracycline, whereas Escherichia coli (14 mg/ml) and Bacillus subtilis (17 mg/ml) were shown to be sensitive to chloramphenicol. The findings of this study indicate that Moringa oleifera leaf extract can be used to uncover antibacterial agents and create new medications for the treatment of common human pathogenic microorganisms that cause specific illnesses. The active substances that are responsible for the antibacterial action should be isolated and characterized in further research. They should also be examined in vivo to assess their toxicity and the ideal dose for application in the future.

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"Comparable Antimicrobial Activity Evaluation of Drumstick (Moringa oleifera Lam.) leaves extract against bacterial isolates", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 7, page no.c325-c327, July-2023, Available :https://ijnrd.org/papers/IJNRD2307231.pdf

Volume 8 Issue 7, July-2023

Pages : c325-c327

Paper Reg. ID: IJNRD_201751

Published Paper Id: IJNRD2307231

Downloads: 000121117

Research Area: Biological Science

Country: HAMIRPUR, HIMACHAL PRADESH, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2307231.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2307231

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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