INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
The current study's goal was to create a sustained release (SR) tablet formulation of glipizide by combining two hydrophobic polymers with two naturally occurring hydrophilic gum resins. The preparation of several batches of Glipizide sustained release tablets moist granulation with lactose and dicalcium phosphate as diluents. The produced pills were assessed based on a number of factors. The commercial Glynase XL pills were compared with the results of an in vitro drug release research. An ideal formulation (SR F3) that contains olibanum resin and lactose as a diluent was discovered to have dissolving profiles that were comparable to those of the reference product. The Korsmeyer and Peppas model provided the best explanation for the kinetics of drug release, and a non-fickian diffusion mechanism was used to release the medication from these tablets. In conclusion, an SR formulation of Glipizide might be created using lactose as a diluent and olibanum resin as a matrix forming that regulates rate.
"FORMULATION AND EVALUATION OF GLIPIZIDE SUSTAINED RELEASE TABLETS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.g110-g121, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306613.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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