INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Tumor targeting drug delivery systems have gained significant attention as a promising approach to improve the efficacy and safety of cancer therapies. This comprehensive review highlights recent developments in this field, encompassing various strategies and advancements. Passive targeting strategies exploit the enhanced permeability and retention effect and size-based targeting for preferential accumulation of drug-loaded carriers in tumors. Active targeting strategies utilize ligand-mediated, antibody-mediated, aptamer-mediated, and nanobody-based approaches to enhance specificity by selectively binding to tumor-specific receptors. Stimuli-responsive targeting strategies, including pH-responsive, enzyme-responsive, and temperature-responsive systems, enable triggered drug release within the tumor microenvironment. Nanoparticle-based drug delivery systems have seen remarkable progress, particularly lipid-based, polymer-based, and metal-based nanoparticles, offering improved drug encapsulation, controlled release, and enhanced targeting capabilities. Notably, nanocarriers designed for nucleic acid delivery, such as lipid nanoparticles for RNA delivery and polymeric nanoparticles for gene delivery, hold great promise for gene-based cancer therapies. .This comprehensive review provides an overview of the recent developments in this field, focusing on various strategies and technologies employed for efficient and specific drug delivery to tumor sites.
" Recent Developments in Tumor Targeting Drug Delivery Systems: A Comprehensive Review", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.e823-e831, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306500.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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