Recent Developments in Tumor Targeting Drug Delivery Systems: A Comprehensive Review

Recent Developments in Tumor Targeting Drug Delivery Systems: A Comprehensive Review

Registration ID: IJNRD_200283

Published ID: IJNRD2306500

DOI: Click Here to Get

Udipta paul , Dhruba kishore paul , Mouly mitra

tumor targeting, drug delivery systems, passive targeting, active targeting, stimuli-responsive, nanoparticle-based, nucleic acid delivery, lipid nanoparticles, polymer-based nanoparticles, metal-based nanoparticles, exosomes, antibody-drug conjugates, peptide-based, characterization techniques, biocompatibility, safety assessment.

Tumor targeting drug delivery systems have gained significant attention as a promising approach to improve the efficacy and safety of cancer therapies. This comprehensive review highlights recent developments in this field, encompassing various strategies and advancements. Passive targeting strategies exploit the enhanced permeability and retention effect and size-based targeting for preferential accumulation of drug-loaded carriers in tumors. Active targeting strategies utilize ligand-mediated, antibody-mediated, aptamer-mediated, and nanobody-based approaches to enhance specificity by selectively binding to tumor-specific receptors. Stimuli-responsive targeting strategies, including pH-responsive, enzyme-responsive, and temperature-responsive systems, enable triggered drug release within the tumor microenvironment. Nanoparticle-based drug delivery systems have seen remarkable progress, particularly lipid-based, polymer-based, and metal-based nanoparticles, offering improved drug encapsulation, controlled release, and enhanced targeting capabilities. Notably, nanocarriers designed for nucleic acid delivery, such as lipid nanoparticles for RNA delivery and polymeric nanoparticles for gene delivery, hold great promise for gene-based cancer therapies. .This comprehensive review provides an overview of the recent developments in this field, focusing on various strategies and technologies employed for efficient and specific drug delivery to tumor sites.

Published Paper   E-Certificate

" Recent Developments in Tumor Targeting Drug Delivery Systems: A Comprehensive Review", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 6, page no.e823-e831, June-2023, Available :https://ijnrd.org/papers/IJNRD2306500.pdf

Volume 8 Issue 6, June-2023

Pages : e823-e831

Paper Reg. ID: IJNRD_200283

Published Paper Id: IJNRD2306500

Downloads: 000121196

Research Area: Pharmacy

Country: Habra, , West Bengal , India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2306500.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2306500

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

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