Paper Title
MONITORING OF ADRS FOR DRUG USES IN MANAGEMENT OF ELEVATED LIVER MARKERS DURING PREGNANCY
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Abstract
The physiological changes in liver function in pregnancy are commonly transient, rarely permanent. Disorders arising in pregnancy, such as pre-eclampsia and eclampsia, acute fatty liver of pregnancy (AFLP), hemolysis, elevated liver enzyme and low platelets (HELLP) syndrome, cholestasis, hyperemesis gravidarum and isolated cases of raised liver enzymes canhave serious implications. Proper interpretation of liver function tests (LFTs) at an early stage can lead to timemanagement and may reduce complications in both mother and fetus. Normal LFTs do not always mean that the liver isnormal. A number of pitfalls can be encountered in the interpretation of basic blood LFTs. The commonly used LFTsprimarily assess liver injury rather than hepatic function. Abnormal LFTs may indicate that something is wrong with theliver, and they can provide clues to the nature of the problem but this is not always the case. The various biochemical tests,their pathophysiology, and an approach to the interpretation of abnormal LFTs are discussed in this review. Commonlyavailable tests includealanine transaminase, aspartate transaminase, alkaline phosphatase, bile acid, serum bilirubin, serumalbumin and prothrombin time. Keywords:Liver function tests, pregnancy, delivery, obstetric
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RITU SHARMA (June-2023). MONITORING OF ADRS FOR DRUG USES IN MANAGEMENT OF ELEVATED LIVER MARKERS DURING PREGNANCY. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), d778-d790. https://ijnrd.org/papers/IJNRD2306381.pdf
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Volume 8 Issue 6, June-2023
Pages : d778-d790
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Paper Reg. ID: IJNRD_199696
Published Paper Id: IJNRD2306381
Downloads: 000122254
Research Area: Pharmacy
Author Type: Indian Author
Country: mathura, uttar pardesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2306381.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2306381
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