Paper Title
A Clinical Study to Assess the Drug Utilization Pattern and Expenditure of Multi-drug Therapy in Breast Cancer Patients
Article Identifiers
Authors
ROHIT KUMAR KUMAWAT , Dr.MAHENDRA KUMAR CHOUHAN , Dr. RAJESH ASIJA
Keywords
cancer, tamoxifan, taxane, letrazole
Abstract
Anticancer drugs resistance is a complex process that arises from altering in the drug Targets. Advances in the DNA microarray, proteomics technology and the development of Targeted therapies provide the new strategies to overcome the drug resistance. Although a design of the new chemotherapy agents is growing quickly, effective chemotherapy agent has not been discovered against the advanced stage of cancer (such as invasion and Metastasis). The cancer cell resistance against the anticancer agents can be due to many Factors such as the individual’s genetic differences, especially in tumoral somatic cells. Also, the cancer drug resistance is acquired, the drug resistance can be occurred by different Mechanisms, including multi-drug resistance, cell death inhibiting (apoptosis suppression), Altering in the drug metabolism, epigenetic and drug targets, enhancing DNA repair and gene amplification. In this review, we outlined the mechanisms of cancer drug resistance and in following, the treatment failures by common chemotherapy agents in the different type of cancers. ________________________________
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How To Cite (APA)
ROHIT KUMAR KUMAWAT, Dr.MAHENDRA KUMAR CHOUHAN, & Dr. RAJESH ASIJA (June-2023). A Clinical Study to Assess the Drug Utilization Pattern and Expenditure of Multi-drug Therapy in Breast Cancer Patients. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), d577-d589. https://ijnrd.org/papers/IJNRD2306360.pdf
Issue
Volume 8 Issue 6, June-2023
Pages : d577-d589
Other Publication Details
Paper Reg. ID: IJNRD_199682
Published Paper Id: IJNRD2306360
Downloads: 000121975
Research Area: Pharmacy
Country: jaipur, rajashtahn, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2306360.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2306360
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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