INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
A Ligand, 1-((2-hydroxy-3-methylphenyl)(piperidin-1-yl)methyl)thiourea was prepared by treating with 2-hydroxy-3-methylbenzaldehyde, piperidine and thiourea. Using the above Schiff’s base ligand, the metal complexes of Cu(II),Co(II).Ni(II),Mn(II), Zn(II) Cd(II) and Hg(II) were prepared. Schiff’s base ligand and its metal complexes were characterized by physical methods such as elemental analysis, melting point, TLC and Spectral method such as IR, 1H NMR, UV-Visible, ESR studies. For the complexes, molar conductivity and Magnetic susceptibility were also been carried out. The electronic spectra, elemental analysis and magnetic moment results proved that the complexes adopted octahedral geometry. The conductance measurement showed that the complexes are non electrolytes proving their non ionic nature. The Schiff’s base ligand and its metal complexes have also been screened for their antimicrobial activity against selected fungi and bacteria. The antimicrobial results indicates that the metal complexes acts as better antimicrobial agents as compared to the Schiff’s base ligands.
Keywords:
Piperidine, Thiourea, IR, 1H NMR, UV-Visible and Microbial activity.
Cite Article:
"Synthesis, Spectral studies and antimicrobial evaluation of 1-((2-hydroxy-3-methylphenyl)(piperidin-1-yl)methyl)thiourea and its Complexes ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.d491-d502, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306350.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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