Synthesis, Spectral studies and antimicrobial evaluation of 1-((2-hydroxy-3-methylphenyl)(piperidin-1-yl)methyl)thiourea and its Complexes

Registration ID: IJNRD_199449

Published ID: IJNRD2306350

DOI: http://doi.one/10.1729/Journal.34776

BASAVARAJ.A.KALOJI , Dr.KASHINATH.G.KANAJE , MD NADEEM MIYAN

Piperidine, Thiourea, IR, 1H NMR, UV-Visible and Microbial activity.

A Ligand, 1-((2-hydroxy-3-methylphenyl)(piperidin-1-yl)methyl)thiourea was prepared by treating with 2-hydroxy-3-methylbenzaldehyde, piperidine and thiourea. Using the above Schiff’s base ligand, the metal complexes of Cu(II),Co(II).Ni(II),Mn(II), Zn(II) Cd(II) and Hg(II) were prepared. Schiff’s base ligand and its metal complexes were characterized by physical methods such as elemental analysis, melting point, TLC and Spectral method such as IR, 1H NMR, UV-Visible, ESR studies. For the complexes, molar conductivity and Magnetic susceptibility were also been carried out. The electronic spectra, elemental analysis and magnetic moment results proved that the complexes adopted octahedral geometry. The conductance measurement showed that the complexes are non electrolytes proving their non ionic nature. The Schiff’s base ligand and its metal complexes have also been screened for their antimicrobial activity against selected fungi and bacteria. The antimicrobial results indicates that the metal complexes acts as better antimicrobial agents as compared to the Schiff’s base ligands.

Published Paper   E-Certificate

BASAVARAJ.A.KALOJI, Dr.KASHINATH.G.KANAJE, & MD NADEEM MIYAN (June-2023). Synthesis, Spectral studies and antimicrobial evaluation of 1-((2-hydroxy-3-methylphenyl)(piperidin-1-yl)methyl)thiourea and its Complexes . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), d491-d502. http://doi.one/10.1729/Journal.34776

Volume 8 Issue 6, June-2023

Pages : d491-d502

Paper Reg. ID: IJNRD_199449

Published Paper Id: IJNRD2306350

Downloads: 000121990

Research Area: Chemistry

Country: KALABURAGI(GULBARGA), KARNATAKA, India

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Crossref DOI: http://doi.one/10.1729/Journal.34776

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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