Physicochemical Standardization and evaluation of Nigella sativa, Moringa olifera and Curcuma longa

Registration ID: IJNRD_199133

Published ID: IJNRD2306259

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varuna, Rajiv Gupta

Nigella sativa, Moringa olifera, Curcuma longa, Herbal plants, Physicochemical Standardization

The use of medicinal plants in both crude and prepared forms has increased greatly. The world health organization has estimated that 80% of the global population relies chiefly on traditional medicine for health care and there are reports that about 51% of all drug preparations in industrialized countries derive from plants, acting as sources of therapeutic agents or models for new synthetic compounds, or as raw material for semisynthetic production of highly complex molecules. The main objective of the proposed study is to formulate and evaluate a herbal dosage form containing extract of plant named Nigella sativa, Moringa olifera and Curcuma longa. The plants will be collected and authenticated. They will be extracted successive solvent extraction followed by preliminary phytochemical evaluation of all the extracts. The extract with potential chemical constituents will be selected for fractionation with various solvents. The traditional literature claims numerous medicinal plants having anti inflammatory potential, however the lack of research studies on these plants make their application in the pharmaceutical industry very insignificant. A number of physicochemical characteristics were calculated, including swelling index, ash content, acid insoluble ash, and water soluble ash extractive value. Nigella sativa, Moringa olifera, and Curcuma longa medication extracts were reported to have ash content values of 7.20 % w/w, 7.13% w/w, 7.06% w/w, and 7.05% w/w, respectively. While Nigella sativa, Moringa olifera, and Curcuma longa medicine extract were found to have water soluble ash contents of 3.92%, 3.94%, 4.23%, and 4.61%, respectively. The yield of the aqueous extract with semisolid masses of brownish, greenish, and bright yellow colours, respectively, was determined to be 6.37, 7.83, and 4.23% w/w of the crude drug. Further studies are required to check the anti inflammatory potential and other pharmacological activity of these plants.

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varuna & Rajiv Gupta (June-2023). Physicochemical Standardization and evaluation of Nigella sativa, Moringa olifera and Curcuma longa. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), c546-c569. https://ijnrd.org/papers/IJNRD2306259.pdf

Volume 8 Issue 6, June-2023

Pages : c546-c569

Paper Reg. ID: IJNRD_199133

Published Paper Id: IJNRD2306259

Research Area: Pharmacy

Author Type: Indian Author

Country: Lucknow, UP, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2306259.pdf

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