THE COMBINATION OF HAGONOY (Chromolaena odorata) LEAF EXTRACTS AND CALAMANSI (Citrus microcarpa) PEEL EXTRACTS WITH LAVENDER SCENT AS AN ALTERNATIVE OPEN-WOUND HEALING CREAM

Registration ID: IJNRD_198911

Published ID: IJNRD2306174

DOI: Click Here to Get

Tito B. Cagang, Jr. , Orly Q. Gantala , Earl Lloyd Z. Fuentes , Nash G. Zulueta , Charisse Mercy T. Esperanza

Hagonoy, Calamansi, Open-Wound, Healing Cream, Lavender Scent, In Vitro Testing, Antibacterial Properties, pH Level, In Vivo Testing, Excised Wound-Healing Evaluation, Percentage of Wound Closure, Area of Wound, Body Weight, Rattus norvegicus, Betadine Cream

This research formulated open-wound healing cream using the quantitative method, specifically the true experimental design. In effectively formulating the product, the researchers adopted but modified the protocol. They combined Olive Oil (80.2g), Coconut Oil (80.24g), Beeswax (36.25g), and Honey (18.15g). Thereafter, the different concentrations of the formulated creams were subjected to in vitro and vivo testing. In vitro testing, the results showed that the product T5 (75% concentration in favor of Citrus microcarpa) produced a satisfactory result by being active in inhibiting S. aureus. Additionally, this formulated product is safe for use on the skin or wounds since its pH level is 4.29 and is within the required range for a wound-healing cream. Furthermore, the in vivo testing, results revealed that the formulated cream (treatment) exhibited more wound healing results than the Betadine cream (positive control). In terms of the wound area, the formulated cream HCO demonstrated the fastest wound-healing activity, compared with the Betadine cream. In terms of body weight, replicates under 75% in favor of Calamansi hCO concentration got the highest difference. Additionally, it was found that there is a significant difference in the mean of inhibitions of different concentrations between control and treatment groups in terms of antibacterial properties and in the size of the wound in terms of different concentrations applied. Conversely, there is no significant difference in the mean weight of sample mice in terms of different concentrations applied. Hence, it is recommended that further testing such as histopathology and tensile strength may be performed to measure the efficacy of the open-wound healing cream.

Published Paper   E-Certificate

Tito B. Cagang, Jr., Orly Q. Gantala, Earl Lloyd Z. Fuentes, Nash G. Zulueta, & Charisse Mercy T. Esperanza (June-2023). THE COMBINATION OF HAGONOY (Chromolaena odorata) LEAF EXTRACTS AND CALAMANSI (Citrus microcarpa) PEEL EXTRACTS WITH LAVENDER SCENT AS AN ALTERNATIVE OPEN-WOUND HEALING CREAM. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), b637-b653. https://ijnrd.org/papers/IJNRD2306174.pdf

Volume 8 Issue 6, June-2023

Pages : b637-b653

Paper Reg. ID: IJNRD_198911

Published Paper Id: IJNRD2306174

Downloads: 000122030

Research Area: Life Sciences 

Country: Maasim 2, Maasim, Philippines

Published Paper PDF: https://ijnrd.org/papers/IJNRD2306174.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2306174

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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