INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Published Paper Details
Paper Title:
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF REMOGLIFLOZINETABONATE AND METFORMIN HCL IN BULK AND PHARMACEUTICAL DOSAGE FORM
Authors Name:
Dr. Sachin S. Rane
, Mr. Tejas A. Chaudhari , Prof. (Dr.) Rajesh Y. Chaudhari , Prof. (Dr.) Vijay R. Patil
A simple, robust, precise, UV spectroscopic method has been developed for the simultaneous estimation of Remogliflozin and metformin in bulk and tablet dosage forms. In this paper the estimation of those drugs was carried out by simultaneous equation method. This method is based on measurement of absorption at 234nm and 258nm i.e, λmax of metformin and Remogliflozin respectively. The linearity observed for Remogliflozin is in the range of 2-10μg/ml and for metformin is in the range of 10-50μg/ml. The accuracy of methods was assessed by recovery studies and was found to be within the range of 99.80% for 99.98% for both Remogliflozin and metformin. The developed methods were validated with respect to linearity, accuracy (recovery), and precision. The method can be employed for estimation of pharmaceutical formulations with no interference from any other excipients and diluents. The results were validated as per ICH guidelines.
Keywords:
Remogliflozin, Metformin, ICH, Validation etc
Cite Article:
"DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF REMOGLIFLOZINETABONATE AND METFORMIN HCL IN BULK AND PHARMACEUTICAL DOSAGE FORM", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.a779-a789, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306090.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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