Paper Title
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF REMOGLIFLOZINETABONATE AND METFORMIN HCL IN BULK AND PHARMACEUTICAL DOSAGE FORM
Article Identifiers
Authors
Dr. Sachin S. Rane , Mr. Tejas A. Chaudhari , Prof. (Dr.) Rajesh Y. Chaudhari , Prof. (Dr.) Vijay R. Patil
Keywords
Remogliflozin, Metformin, ICH, Validation etc
Abstract
A simple, robust, precise, UV spectroscopic method has been developed for the simultaneous estimation of Remogliflozin and metformin in bulk and tablet dosage forms. In this paper the estimation of those drugs was carried out by simultaneous equation method. This method is based on measurement of absorption at 234nm and 258nm i.e, λmax of metformin and Remogliflozin respectively. The linearity observed for Remogliflozin is in the range of 2-10μg/ml and for metformin is in the range of 10-50μg/ml. The accuracy of methods was assessed by recovery studies and was found to be within the range of 99.80% for 99.98% for both Remogliflozin and metformin. The developed methods were validated with respect to linearity, accuracy (recovery), and precision. The method can be employed for estimation of pharmaceutical formulations with no interference from any other excipients and diluents. The results were validated as per ICH guidelines.
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How To Cite (APA)
Dr. Sachin S. Rane, Mr. Tejas A. Chaudhari, Prof. (Dr.) Rajesh Y. Chaudhari, & Prof. (Dr.) Vijay R. Patil (June-2023). DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF REMOGLIFLOZINETABONATE AND METFORMIN HCL IN BULK AND PHARMACEUTICAL DOSAGE FORM. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(6), a779-a789. https://ijnrd.org/papers/IJNRD2306090.pdf
Issue
Volume 8 Issue 6, June-2023
Pages : a779-a789
Other Publication Details
Paper Reg. ID: IJNRD_198527
Published Paper Id: IJNRD2306090
Downloads: 000121982
Research Area: Pharmacy
Country: Jalgaon, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2306090.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2306090
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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