MUCOADHESIVE DRUG DELIVERY SYSTEM

MUCOADHESIVE DRUG DELIVERY SYSTEM

Registration ID: IJNRD_197932

Published ID: IJNRD2305937

DOI: Click Here to Get

KRUSHNA EKNATH MALAVADE , A. S. SANAP , DR.PRACHI UDAPURKAR

Mucoadhesion, theories, mucoadhesive dosage forms

Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, factors influencing the mucoadhesive devices and also various mucoadhesive dosage forms. A new drug delivery system was developed utilizing both the concept of controlled release and mucoadhesiveness.so as to get unique drug delivery system which could remains in close contact with the absorption the mucus membrane.releasing the drug at the positioning resulting in improvement in both local and systemic effect and controlled the drug release for extended period of your time like different route of mucoadhesive drug delivery,the oral route is most desired by patient. Although preoral administration of drug shows various disadvantages like hepatic first - pass metabolism and enzymatic degradation within alimentary canal, that prohibit oral administration of certain classes of medication especially protein and peptides.

Published Paper   E-Certificate

"MUCOADHESIVE DRUG DELIVERY SYSTEM", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 5, page no.j161-j169, May-2023, Available :https://ijnrd.org/papers/IJNRD2305937.pdf

Volume 8 Issue 5, May-2023

Pages : j161-j169

Paper Reg. ID: IJNRD_197932

Published Paper Id: IJNRD2305937

Downloads: 000121198

Research Area: Pharmacy

Country: Ahmadnagar, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2305937.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2305937

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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