INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
A simple, rapid and precise reversed – phase High performance liquid chromatographic (RP-HPLC) stability indicating method was developed and validated for the determination of Evogliptin in the bulk and tablets. The method involves the use of commonly available and inexpensive laboratory reagents. Chromatographic separation of evogliptin was achieved using a reverse phase Zodiac C18 column (150mm × 4.6mm, 5µm) and Solvent A, 20mM KH2PO4 water-methanol (70:30%, v/v); Solvent B, acetonitrile-methanol (90:10, v/v) as mobile phase at 1.0 ml/min flow rate. Detection was carried out at 260 nm. Rt was found to be 3.463 min for Evogliptin tartrate in stability indicating method different stress conditions were applied.
Keywords:
Evogliptin, High Performance liquid Chromatography, Method Validation, Stability Indicating, Forced degradation study, ICH guidelines.
Cite Article:
"DEVELOPMENT AND VALIDATION OF EVOGLIPTIN IN BULK AND PHARMACEUTICAL DOSAGE FORM AND ITS STRESS DEGRADATION STUDIES", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.i780-i787, May-2023, Available :http://www.ijnrd.org/papers/IJNRD2305890.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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