A Study On the Management of Kidney Disease Associated with COVID-19 in a Tertiary Care Hospital

Registration ID: IJNRD_197306

Published ID: IJNRD2305877

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Thahaniya Salim KP , Sneha PV , Muhammed Fazil AC , Afrah CM , Soumya MK

Kidney disease associated with COVID-19 Management, Age wise distribution, GFR less than 15 ml/min, Kidney disease stage, Dialysis frequency, Oxygen saturation, respiratory rate prediction in COVID-19, Supportive cares given, Mortality rate.

Aim: To study the management of Kidney-disease associated with COVID-19 in patients admitted to the department of nephrology in a tertiary care hospital. Methodology: A prospective observational study was conducted over 6 months among 102 patients. Materials and Methods: All the data are collected, entered, and documented into the Excel sheet based on the protocol. The collected data was Statistically Analysed using Microsoft Excel and SPSS software. Results: Out of 102 population diagnosed with kidney disease with COVID-19, the majority of the patients were male, the study contains 67% of male patients. Disease conditions were commonly seen among the age group of 51-70 years. Major co-morbidities associated were hypertension. Patients suffered most commonly from fever. In our study, most of the Kidney patients had the mild category of COVID-19 which is Category C of COVID-19. We also did a study comparing oxygen saturation level with that of respiratory rate in patients with COVID 19 and mortality rate was found more among patients with decreased oxygen level and increased respiratory rate. Among the admitted patients, the majority of them belonged to stage 5 of CKD. Stage determination of CKD was done on the basis of calculated GFR value. The majority of patients fall under the GFR category of less than 15 ml/min. As patients were suffering from kidney disease dialysis was done, most commonly with the frequency of 3 times a week with a duration of 4 hours. Different categories of drugs like Vitamin supplements, Antibiotics, Antivirals, Corticosteroids, Erythropoiesis stimulating agents, Iron supplements, Anticoagulants, Diuretics, Inotropes, and Monoclonal antibodies were prescribed in our study, out of which Vitamin supplements were given the most among the 102 hospitalized patients. Among Vitamin supplements, Vitamin B Complex with Vitamin B 12, Penicillin and beta-lactamase inhibitors Piperacillin and Tazobactam among antibiotics, Ritonavir among antivirals, Regular heparin among anticoagulants, Iron sucrose among Iron supplements, Methylprednisolone among Corticosteroids, Torsemide among diuretics, Erythropoietin among Erythropoiesis Stimulating Agents, Adrenaline among Inotropes, Casirivimab + Imdevimab among Monoclonal Antibody Supportive care like Oxygen support, ICU, mechanical ventilation, and NIV was given. Most of the patients required oxygen support. During hospitalization, 27 out of 102 patients were dead. Conclusion: The emergence of COVID-19 required the emergency attention of the healthcare system as the etiology and pathophysiology of the disease were unknown at the beginning. All the initial steps of therapy and supportive care given in our study evaluated that it reduced hospitalization and mortality rate among the patients.

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Thahaniya Salim KP, Sneha PV, Muhammed Fazil AC, Afrah CM, & Soumya MK (May-2023). A Study On the Management of Kidney Disease Associated with COVID-19 in a Tertiary Care Hospital. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(5), i682-i701. https://ijnrd.org/papers/IJNRD2305877.pdf

Volume 8 Issue 5, May-2023

Pages : i682-i701

Paper Reg. ID: IJNRD_197306

Published Paper Id: IJNRD2305877

Downloads: 000121976

Research Area: Pharmacy

Country: Kannur, Kerala, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2305877.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2305877

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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