Novel Analytical Design of Ganciclovir

Registration ID: IJNRD_195140

Published ID: IJNRD2305352

DOI: Click Here to Get

jose gnana babu

Ganciclovir, HPTLC, Validation, Capsule dosage form.

A rapid, simple, precise and accurate high performance thin layer chromatographic method has been developed and validated for the estimation of Ganciclovir in bulk and capsule dosage form. The Ganciclovir was chromatographed on silica gel 60 F254 HPTLC plate as a stationary phase. The mobile phase was ethyl acetate: methanol: gla.acetic acid in the volume ratio of 6.0:2:0:2.0 respectively. It gave a dense and compact spot of Ganciclovir with an Rf value of 0.36. The quantitation was carried out at 250 nm. The method was validated in terms of linearity, accuracy, precision and specificity. The statistical analysis proved that the developed method is accurate and reproducible with linearity in the range of 100 to 500 ng/spot. The limit of detection and limit of quantitation for Ganciclovir were 30 and 90 ng/spot respectively. The developed method can be employed for the routine analysis of Ganciclovir in the capsule dosage form.

Published Paper   E-Certificate

jose gnana babu (May-2023). Novel Analytical Design of Ganciclovir. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(5), d385-d388. https://ijnrd.org/papers/IJNRD2305352.pdf

Volume 8 Issue 5, May-2023

Pages : d385-d388

Paper Reg. ID: IJNRD_195140

Published Paper Id: IJNRD2305352

Downloads: 000121999

Research Area: Pharmacy

Country: bengaluru, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2305352.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2305352

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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