Paper Title
EVALUATION OF ANTIBIOTIC PRESCRIPTION PATTERN USING WHO AWaRe CLASSIFICATION AND ANTIBIOTICS DOSAGE ADJUSTMENT IN PATIENTS WITH CHRONIC KIDNEY DISEASE
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Registration ID: IJNRD_194006
Published ID: IJNRD2305151
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Keywords
Chronic Kidney Disease, AWaRe classification, Dosage adjustment, Antibiotics, World Health Organisation
Abstract
Irrational antibiotic therapy cause bacterial resistance, increase side effects of drugs, increase morbidity, increase total hospital costs. The Access, Watch, Reserve (AWaRe) classification of antibiotics formulated by World Health Organisation with the goals of better accessibility and clinical outcomes, a decreased probability of antimicrobial resistance, safeguarding the effectiveness of last-resort antibiotics and to evaluate the rational use of antibiotics. In this study a retrospective observational analysis was conducted over a period of six months in a tertiary care hospital. The objectives of the study was to evaluate the dosage adjustments of antibiotics in chronic kidney disease using Cockcroft – Gault formula and to examine prescription pattern of antibiotics using AWaRe classification of WHO. A total of 100 patient case records satisfying the inclusion criteria were analysed. High consumption of watch-group antibiotics was observed in the study. Ceftriaxone+ sulbactam was the most commonly prescribed antibiotic followed by cefixime. There were 13 irrational antibiotics prescribed in the study population, which are Inj. Piperacillin + Tazobactam , Tab. Cefixime, Inj. Imipenem, Inj. Ceftriaxone etc. Incidence of irrational dosage promotes the need for individualized dosage regimen to patients with Chronic Kidney Disease. Understanding and implementation of dosage adjustment is important to avoid drug toxicity.
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How To Cite (APA)
Jyothy A, Devika S, Sharon Emilia James, Dr Akhila S Arjun, & Dr Anitha Mary Mathews (May-2023). EVALUATION OF ANTIBIOTIC PRESCRIPTION PATTERN USING WHO AWaRe CLASSIFICATION AND ANTIBIOTICS DOSAGE ADJUSTMENT IN PATIENTS WITH CHRONIC KIDNEY DISEASE. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(5), b397-b405. https://ijnrd.org/papers/IJNRD2305151.pdf
Issue
Volume 8 Issue 5, May-2023
Pages : b397-b405
Other Publication Details
Paper Reg. ID: IJNRD_194006
Published Paper Id: IJNRD2305151
Research Area: Pharmacy
Author Type: Indian Author
Country: Pathanamthitta , KERALA, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2305151.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2305151
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