EVALUATION OF ANTIBIOTIC PRESCRIPTION PATTERN USING WHO AWaRe CLASSIFICATION AND ANTIBIOTICS DOSAGE ADJUSTMENT IN PATIENTS WITH CHRONIC KIDNEY DISEASE

EVALUATION OF ANTIBIOTIC PRESCRIPTION PATTERN USING WHO AWaRe CLASSIFICATION AND ANTIBIOTICS DOSAGE ADJUSTMENT IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Registration ID: IJNRD_194006

Published ID: IJNRD2305151

DOI: Click Here to Get

Jyothy A , Devika S , Sharon Emilia James , Dr Akhila S Arjun , Dr Anitha Mary Mathews

Chronic Kidney Disease, AWaRe classification, Dosage adjustment, Antibiotics, World Health Organisation

Irrational antibiotic therapy cause bacterial resistance, increase side effects of drugs, increase morbidity, increase total hospital costs. The Access, Watch, Reserve (AWaRe) classification of antibiotics formulated by World Health Organisation with the goals of better accessibility and clinical outcomes, a decreased probability of antimicrobial resistance, safeguarding the effectiveness of last-resort antibiotics and to evaluate the rational use of antibiotics. In this study a retrospective observational analysis was conducted over a period of six months in a tertiary care hospital. The objectives of the study was to evaluate the dosage adjustments of antibiotics in chronic kidney disease using Cockcroft – Gault formula and to examine prescription pattern of antibiotics using AWaRe classification of WHO. A total of 100 patient case records satisfying the inclusion criteria were analysed. High consumption of watch-group antibiotics was observed in the study. Ceftriaxone+ sulbactam was the most commonly prescribed antibiotic followed by cefixime. There were 13 irrational antibiotics prescribed in the study population, which are Inj. Piperacillin + Tazobactam , Tab. Cefixime, Inj. Imipenem, Inj. Ceftriaxone etc. Incidence of irrational dosage promotes the need for individualized dosage regimen to patients with Chronic Kidney Disease. Understanding and implementation of dosage adjustment is important to avoid drug toxicity.

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"EVALUATION OF ANTIBIOTIC PRESCRIPTION PATTERN USING WHO AWaRe CLASSIFICATION AND ANTIBIOTICS DOSAGE ADJUSTMENT IN PATIENTS WITH CHRONIC KIDNEY DISEASE", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 5, page no.b397-b405, May-2023, Available :https://ijnrd.org/papers/IJNRD2305151.pdf

Volume 8 Issue 5, May-2023

Pages : b397-b405

Paper Reg. ID: IJNRD_194006

Published Paper Id: IJNRD2305151

Downloads: 000121180

Research Area: Pharmacy

Country: Pathanamthitta , KERALA, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2305151.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2305151

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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