Kisspeptin : A Teen Gene Role Beyond The Brain

Registration ID: IJNRD_193796

Published ID: IJNRD2305120

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Deepika R, Dr.G.Venkatesh, Chandrasekar.V, Sneha.K.K, Moganthan.R

Kisspeptin, KISS1 gene, KISSR, hypothalamus, LH, FSH, POA, AVPV

Kisspeptin gene is principal regulator for secretion of gonadotropin releasing hormone from hypothalamus, critical for puberty onset. Anteroventral and arcuate periventricular nuclei of hypothalamus express kisspeptin and their receptors. Kisspeptin's with KISS1R causes changes in hypothalamus cells by turning on phospholipase C. Countless studies have manifested KISS signalling system in numerous peripheral sites linking to biological processes, including regulation of pubertal onset, follicular development, oocyte maturation, ovulation, pregnancy, IVF treatment, lactation, testicular tissues, spermatogenesis, testicular steroidogenesis, pancreas and glucose metabolism, angiogenesis, liver and kidney functions. Researchers found various mechanism, pathology of Kisspeptin other than brain system using KISS1 and KISSR lacking animals. This review gives insights of above discussed contents, its physiological functions outside the brain. Also, future aspects of Kisspeptin gene.

Published Paper   E-Certificate

Deepika R, Dr.G.Venkatesh, Chandrasekar.V, Sneha.K.K, & Moganthan.R (May-2023). Kisspeptin : A Teen Gene Role Beyond The Brain. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(5), b119-b136. https://ijnrd.org/papers/IJNRD2305120.pdf

Volume 8 Issue 5, May-2023

Pages : b119-b136

Paper Reg. ID: IJNRD_193796

Published Paper Id: IJNRD2305120

Downloads: 000122253

Research Area: Pharmacy

Author Type: Indian Author

Country: chennai-600019, Tamil Nadu, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2305120.pdf

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