Paper Title
An Assessment on Emphasis of Chlorpyrifos on Human Health and Environment
Article Identifiers
Authors
MANISHA RANI , DR. SUNIL KUMAR SINGH , DR. ASHOK KUMAR THAKUR
Keywords
Chlorpyrifos (CPF); Organophosphate; toxic effect; human health; environment;
Abstract
Among the organophosphate pesticides Chlorpyrifos (CPF) is one of the oldest, wide-spectrum insecticides, used in public health and residential to kill a variety of insects and control the vectors of diseases. Although, the primary toxicity associated with CPF is cholinergic symptoms resulting from acetylcholinesterase inhibition and consequent accumulation of CPF in the body causes toxic effects on the different systems of exposed living beings, such as muscular, nervous, immune, and endocrine alterations. Several studies have reported that CPF has the potential to induce ROS (Reactive Oxygen Species), lipid peroxidation, and enzyme inactivation of cellular membranes through various biochemical processes, and the metabolites produces by the oxidation of CPF show a pattern of induction of chromosome damage and has been related to mutagenicity, carcinogenicity, teratogenicity, and DNA abnormalities. CPF induces toxicity in soil, air as well as water by decreasing their nutrients. In plants, CPF reduces carbon dioxide assimilation ability, and the nitrogen fixation rate also disrupts the chlorophyll biosynthesis pathway. It is also hepatotoxic, genotoxic as well as renal toxic in mammals and shows a large toxic impact on the male reproductive system. This review is based on scientific reports, data, and previous research that had been done in previous years which explain the toxic effect of CPF in a complete environment, in both abiotic and biotic factors, and show the risk to human health due to the use of CPF. KEYWORDS: Chlorpyrifos (CPF); Organophosphate; toxic effect; human health; environment;
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How To Cite (APA)
MANISHA RANI, DR. SUNIL KUMAR SINGH, & DR. ASHOK KUMAR THAKUR (April-2023). An Assessment on Emphasis of Chlorpyrifos on Human Health and Environment. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(4), f548-f554. https://ijnrd.org/papers/IJNRD2304563.pdf
Issue
Volume 8 Issue 4, April-2023
Pages : f548-f554
Other Publication Details
Paper Reg. ID: IJNRD_192446
Published Paper Id: IJNRD2304563
Downloads: 000121977
Research Area: Life SciencesÂ
Country: bhagalpur, bihar, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2304563.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2304563
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