A REVIEW - THYROIDISM

Registration ID: IJNRD_190730

Published ID: IJNRD2304158

DOI: Click Here to Get

Ms. Vidya Barhate , Dr. Hemant v. Kambale , Prof. Santosh A. Waghmare , Ms. Aishwarya Bhandari

Hyperthyroidism , Hypothyroidism , Thyroid Hormone

Hypothyroidism is a common condition in which the thyroid gland provides insufficient amounts of thyroid hormone for the needs of peripheral tissues. The most common cause in adults is chronic lymphocytic thyroiditis (Hashimoto thyroiditis), but there are many other causes. Because most of the clinical features of hypothyroidism are nonspecific, the diagnosis requires laboratory testing. Serum thyroid-stimulating hormone (TSH) measurement is the best diagnostic test; an elevated TSH level almost always signals primary hypothyroidism. Serum free thyroxine levels may be below the reference range (overt hypothyroidism) or within the reference range (subclinical hypothyroidism). All patients with overt hypothyroidism should be treated, but those with subclinical hypothyroidism do not always benefit from treatment, especially elderly patients and those with baseline TSH levels below 10 mU/L. Oral L-thyroxine is the treatment of choice because of its well-demonstrated efficacy, safety, and ease of use. Therapy goals are symptom relief and maintenance of serum TSH levels within the reference range. Myxedema coma is a life-threatening form of decompensated hypothyroidism that must be treated with aggressive L-thyroxine replacement and other supportive measures in the inpatient setting. Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference. This article describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist and subspeciality. According to common perception, hypothyroidism is held responsible for obesity. However, linking them causally is controversial. Overt hypothyroidism is associated with modest weight gain, but there is a lack of clarity regarding subclinical hypothyroidism. Novel view indicates that changes in thyroid-stimulating hormone (TSH) could well be secondary to obesity. The increasing prevalence of obesity further confounds definition of normal TSH range in population studies. Thyroid autoantibody status may help in establishing the diagnosis of subclinical hypothyroidism

Published Paper   E-Certificate

Ms. Vidya Barhate, Dr. Hemant v. Kambale, Prof. Santosh A. Waghmare , & Ms. Aishwarya Bhandari (April-2023). A REVIEW - THYROIDISM. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(4), b484-b491. https://ijnrd.org/papers/IJNRD2304158.pdf

Volume 8 Issue 4, April-2023

Pages : b484-b491

Paper Reg. ID: IJNRD_190730

Published Paper Id: IJNRD2304158

Downloads: 000121978

Research Area: Pharmacy

Country: Pune , Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2304158.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2304158

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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