INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
The ethnomedicinal usage of Bryophyllum pinnatum leaves in urinary problems was validated by their ability to inhibit the development of renal calculi. Also it backs up their therapeutic potential to treat kidney stones. Mine goal in developing a polymeric microsponge delivery system would have been to equally spread Bryophyllum pinatum over a long period of time, reduce administration frequency, and maximise bioavailability. These Microsponges are then placed within capsules of the "1" size. As both a consequence, Bryophyllum Microsponges capsules were produced employing a simple, reproducible, yet quick quasiemulsion solvent diffusion strategy in this study. Inside the prepared Microsponges, FTIR, SEM, drug content, particle size analysis, as well as loading yield were determined. Bryophyllum microsponges were again embedded in kidney stones to test their release. The particle size , drug release behaviour of both the generated Microsponges were demonstrated to be regulated by the drug polymer ratios, stirring rate, that volume of dispersed phase, but that the presence of the an emulsifier was required for microsponge production. These findings revealed that increasing overall drug-polymer ratio resulted in a decrease with in release rate of Microsponges capsules, that was attributable towards the Microsponges' internal porosity.
Keywords:
Microsponges delivery system, Control release, Oral drug delivery system,Quasi-emulsion solvent diffusion, Byrophyllum pinnatum.
Cite Article:
"FORMULATION AND EVALUATION OF HERBAL LOADED MICROSPONGES CAPSULES", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 3, page no.d363-d376, March-2023, Available :http://www.ijnrd.org/papers/IJNRD2303348.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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