FORMULATION AND EVALUATION OF HERBAL LOADED MICROSPONGES CAPSULES

FORMULATION AND EVALUATION OF HERBAL LOADED MICROSPONGES CAPSULES

Registration ID: IJNRD_187513

Published ID: IJNRD2303348

DOI: Click Here to Get

Neeraj kumar , .DR. MD.SEMIMUL AKHTAR

Microsponges delivery system, Control release, Oral drug delivery system,Quasi-emulsion solvent diffusion, Byrophyllum pinnatum.

The ethnomedicinal usage of Bryophyllum pinnatum leaves in urinary problems was validated by their ability to inhibit the development of renal calculi. Also it backs up their therapeutic potential to treat kidney stones. Mine goal in developing a polymeric microsponge delivery system would have been to equally spread Bryophyllum pinatum over a long period of time, reduce administration frequency, and maximise bioavailability. These Microsponges are then placed within capsules of the "1" size. As both a consequence, Bryophyllum Microsponges capsules were produced employing a simple, reproducible, yet quick quasiemulsion solvent diffusion strategy in this study. Inside the prepared Microsponges, FTIR, SEM, drug content, particle size analysis, as well as loading yield were determined. Bryophyllum microsponges were again embedded in kidney stones to test their release. The particle size , drug release behaviour of both the generated Microsponges were demonstrated to be regulated by the drug polymer ratios, stirring rate, that volume of dispersed phase, but that the presence of the an emulsifier was required for microsponge production. These findings revealed that increasing overall drug-polymer ratio resulted in a decrease with in release rate of Microsponges capsules, that was attributable towards the Microsponges' internal porosity.

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"FORMULATION AND EVALUATION OF HERBAL LOADED MICROSPONGES CAPSULES", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 3, page no.d363-d376, March-2023, Available :https://ijnrd.org/papers/IJNRD2303348.pdf

Volume 8 Issue 3, March-2023

Pages : d363-d376

Paper Reg. ID: IJNRD_187513

Published Paper Id: IJNRD2303348

Downloads: 000121150

Research Area: Pharmacy

Country: BAREILLY, Uttar Pradesh, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2303348.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2303348

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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