preliminary phytochemical screening, in-vitro antibacterial and anthelmintic activities of ethanolic extract of peperomia pellucida

Registration ID: IJNRD_188618

Published ID: IJNRD2303149

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Jayalekshmi.M

peperomia pellucida, antibacterial activity, anthelmintic activity, preliminary phytochemical screening

Antibacterial and anthelmintic activities of plants are being increasingly reported from different parts of the world. The main aim of this study is to investigate preliminary phytochemical screening, antibacterial and anthelmintic activity of ethanolic extract of peperomia pellucida. Antibacterial activity was evaluated by using agar cup plate method at different concentrations (100mg/ml, 300mg/ml and 500mg/ml) of extract and the results were compared with gentamycin (standard antibiotic). Zone of inhibition formed after 48hrs and proved that it has good antibacterial activity. Anthelmintic activity was evaluated by using Indian adult earth worms (pheritima posthuma) because they posses anatomical and physical resemblance of intestinal round worm. Earth worms were collected and washed in normal saline solution then released in different concentrations (100mg/ml, 200mg/ml, 500mg/ml and 1000mg/ml) of ethanolic extract of peperomia pellucida and in standard albendazole. Time taken for the paralysis and time taken for the death of the earth worms were noted. So the extract exhibited mild anthelmintic activity. Preliminary phytochemical analysis of the extract showed the presence of alkaloids, flavonoids and tannins. Tannins have been outlined as having anthelmintic activity. İt can bind to free proteins in the gut of the host or glycoprotein on the cuticle of the parasite and this leads to death of parasite.

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Jayalekshmi.M (March-2023). preliminary phytochemical screening, in-vitro antibacterial and anthelmintic activities of ethanolic extract of peperomia pellucida. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(3), b429-b436. https://ijnrd.org/papers/IJNRD2303149.pdf

Volume 8 Issue 3, March-2023

Pages : b429-b436

Paper Reg. ID: IJNRD_188618

Published Paper Id: IJNRD2303149

Downloads: 000122021

Research Area: Pharmacy

Author Type: Indian Author

Country: Thiruvananthapuram, kerala, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2303149.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2303149

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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