INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
New compounds were synthesized containing novel hydantoin derivatives and tested for their antimicrobial activity against gram positive and gram negative strains. The scheme was adopted for the synthesis of phenothiazine derivatives is done via thionation of aryl amines. Total five compounds were synthesized and characterization was done using various physical and spectral techniques such as Thin Layer Chromatography, Melting point ,Solubility determination, UV spectroscopy and FTIR spectroscopy and 1HNMR spectroscopy. All the synthesized compounds were biologically evaluated for in-vitro antimicrobial activity against gram positive and gram negative bacteria by well diffusion method. The in-vitro evaluation of the synthesized compounds was performed by taking gram positive bacteria Staphylococcus Aureus and gram negative bacteria Escherichia Coli. The antibacterial activity of phenothiazine derivatives showed significant zone of inhibition against both bacterias. Thus from the study it is concluded that these new hydration derivatives could serve as effective antimicrobial agents.
"SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF NOVEL PHENOTHIAZINE DERIVATIVES", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 2, page no.c708-c713, February-2023, Available :http://www.ijnrd.org/papers/IJNRD2302278.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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