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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Impact Factor : 8.76

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Paper Title: DIAGNOSIS OF PRIMARY MYELOFIBROSIS PRE-FIBROTIC PHASE-(A Rare case report)
Authors Name: Dr.G K Parvathidevi , Dr.Ramesh S T
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IJNRD_187843
Published Paper Id: IJNRD2302253
Published In: Volume 8 Issue 2, February-2023
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Abstract: Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm (MPN) characterized by a proliferation of prodominently megakaryocytes and granulocytes in the bone marrow that in fully developed disease is associated with reactive deposition of fibrous connective tissue and with extramedullary haematopoiesis(EMF)(1). There is a stepwise evolution from an initial pre-fibrotic phase charecterised by a hypercellular marrow with absent or minimal reticulin fibrosis to a fibrotic phase with marked reticulin collagen fibrosis in the marrowand often sclerosis.  The synonyms for PMF include- Chronic idiopathic myelofirbosis (CIMF); Agnogenic myeloid metaplasia (AMM); Myelofibrosis /sclerosis with myeloid metaplasia (MMM); Idiopathic myelofibrosis; Myeloid megakaryocytic granulocytic metaplasia (MMGM); and many others(2). Literature search revealed three study groups comprising of 1247 cases of pre-fibrotic phase of primay myelobrosis (3,4,5). We could not find any single case reports. We report here the peripheral smear findings,bone marrow examination findings, cytogenetic abnormality in a case of prefibrotic phase of primary myelofibrosis in a 70 year old male patient, who presented with pain abdomen.
Keywords: myelofibrosis,myeloproliferative,neoplasm
Cite Article: "DIAGNOSIS OF PRIMARY MYELOFIBROSIS PRE-FIBROTIC PHASE-(A Rare case report)", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 2, page no.c459-c472, February-2023, Available :http://www.ijnrd.org/papers/IJNRD2302253.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2302253
Registration ID: 187843
Published In: Volume 8 Issue 2, February-2023
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Page No: c459-c472
Country: Tumkur, Karnataka, India
Research Area: Health Science 
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2302253
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2302253
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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