Study of pharmacovigilance related drug Caffeine

Registration ID: IJNRD_186038

Published ID: IJNRD2301150

DOI: Click Here to Get

Rajesh S Pawade , Mahesh R Gore , Ajit D Nagare , Yogesh J Musale , Shankar D Gore

Pharmacovigilance, toxicology, cervical cancer, human papillomavirus, Caffeine

Pharmacovigilance (PV or PhV), also known as Drug Safety, is the pharmacological science relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. Caffeine, a component of coffee, soft drinks, and chocolate, is widely consumed and considered harmless, although it has powerful effects on a number of organs, systems, and behavior. Caffeine, in typical concentration ranges of human consumption, acts as a nonspecific blocker of the adenosine receptor. Caffeine is the most widely consumed behaviorally active substance in the world. The behavioral effects of caffeine have been reviewed many times (e.g., Lieberman, 1992; Fredholm et al., 1999; Smith, 2002) and this chapter overviews the main findings and provides an update of recent research. Caffeine produces its behavioral effects through adenosine receptor antagonism and subsequent changes in many neurotransmitter systems. This result in increased alertness and caffeine may be especially beneficial in low arousal situations (e.g., working at night, prolonged work, or sleep deprivation). It improves performance on tasks that are impaired when alertness is low (vigilance and sustained response). Such effects largely reflect increased turnover of central noradrenaline. Although it has strong impacts on a number of organs, systems, and behaviours, caffeine, an ingredient in coffee, soft drinks, and chocolate, is frequently ingested and perceived as innocuous. When consumed in typical human concentration ranges, caffeine serves as an all-purpose adenosine receptor blocker.

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Rajesh S Pawade, Mahesh R Gore, Ajit D Nagare, Yogesh J Musale, & Shankar D Gore (January-2023). Study of pharmacovigilance related drug Caffeine. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(1), b427-b443. https://ijnrd.org/papers/IJNRD2301150.pdf

Volume 8 Issue 1, January-2023

Pages : b427-b443

Paper Reg. ID: IJNRD_186038

Published Paper Id: IJNRD2301150

Downloads: 000121982

Research Area: Pharmacy

Country: Ahmednagar, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2301150.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2301150

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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