Paper Title
Study of pharmacovigilance related drug Caffeine
Article Identifiers
Authors
Rajesh S Pawade , Mahesh R Gore , Ajit D Nagare , Yogesh J Musale , Shankar D Gore
Keywords
Pharmacovigilance, toxicology, cervical cancer, human papillomavirus, Caffeine
Abstract
Pharmacovigilance (PV or PhV), also known as Drug Safety, is the pharmacological science relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. Caffeine, a component of coffee, soft drinks, and chocolate, is widely consumed and considered harmless, although it has powerful effects on a number of organs, systems, and behavior. Caffeine, in typical concentration ranges of human consumption, acts as a nonspecific blocker of the adenosine receptor. Caffeine is the most widely consumed behaviorally active substance in the world. The behavioral effects of caffeine have been reviewed many times (e.g., Lieberman, 1992; Fredholm et al., 1999; Smith, 2002) and this chapter overviews the main findings and provides an update of recent research. Caffeine produces its behavioral effects through adenosine receptor antagonism and subsequent changes in many neurotransmitter systems. This result in increased alertness and caffeine may be especially beneficial in low arousal situations (e.g., working at night, prolonged work, or sleep deprivation). It improves performance on tasks that are impaired when alertness is low (vigilance and sustained response). Such effects largely reflect increased turnover of central noradrenaline. Although it has strong impacts on a number of organs, systems, and behaviours, caffeine, an ingredient in coffee, soft drinks, and chocolate, is frequently ingested and perceived as innocuous. When consumed in typical human concentration ranges, caffeine serves as an all-purpose adenosine receptor blocker.
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"Study of pharmacovigilance related drug Caffeine", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 1, page no.b427-b443, January-2023, Available :https://ijnrd.org/papers/IJNRD2301150.pdf
Issue
Volume 8 Issue 1, January-2023
Pages : b427-b443
Other Publication Details
Paper Reg. ID: IJNRD_186038
Published Paper Id: IJNRD2301150
Downloads: 000121145
Research Area: Pharmacy
Country: Ahmednagar, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2301150.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2301150
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition


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