NEPHROTOXICITY

Registration ID: IJNRD_185657

Published ID: IJNRD2301055

: http://doi.one/10.1729/Journal.32604

MINAKSHI

Nephrotoxicity is characterized by any adverse functional or structural change in the kidney due to the effect of chemical or biological product, that is inhaled, ingested or absorbed or which yields metabolite with an identifiable toxic effect on the kidney(Aslam et al., 2013 ) A number of therapeutic agents can adversely affect the kidney resulting in acute renal failure, chronic interstitial nephritis and nephritic syndrome. The usage of certain drugs in the long run may lead to nephrotoxicity as these drugs tend to get accumulated in the form of by-products which lead to renal failure.( Aslam et al., 2013 ) Nephrotoxic drugs include antiretrovirals (example, tenofovir), antimicrobials (example, aminoglycosides) and chemotherapeutic agents (example, cisplatin) (Perazella, 2009). These drugs induce their nephrotoxicity on the tubular, glomerular, interstitial or vascular components of the kidneys. Toxicity of drugs on renal tubular cells is enhanced by the impairment of mitochondrial function, tubular transport interference, increase in oxidative stress and formation of free radicals

Published Paper   E-Certificate

MINAKSHI (January-2023). NEPHROTOXICITY. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(1), a478-a479. http://doi.one/10.1729/Journal.32604

Volume 8 Issue 1, January-2023

Pages : a478-a479

Paper Reg. ID: IJNRD_185657

Published Paper Id: IJNRD2301055

Downloads: 000122032

Research Area: Pharmacy

Author Type: Indian Author

Country: jhajjar, Haryana, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2301055.pdf

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Crossref DOI: http://doi.one/10.1729/Journal.32604

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