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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | NEPHROTOXICITY |
| Authors Name: | MINAKSHI |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_185657
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| Published Paper Id: | IJNRD2301055 |
| Published In: | Volume 8 Issue 1, January-2023 |
| DOI: | http://doi.one/10.1729/Journal.32604 |
| Abstract: | Nephrotoxicity is characterized by any adverse functional or structural change in the kidney due to the effect of chemical or biological product, that is inhaled, ingested or absorbed or which yields metabolite with an identifiable toxic effect on the kidney(Aslam et al., 2013 ) A number of therapeutic agents can adversely affect the kidney resulting in acute renal failure, chronic interstitial nephritis and nephritic syndrome. The usage of certain drugs in the long run may lead to nephrotoxicity as these drugs tend to get accumulated in the form of by-products which lead to renal failure.( Aslam et al., 2013 ) Nephrotoxic drugs include antiretrovirals (example, tenofovir), antimicrobials (example, aminoglycosides) and chemotherapeutic agents (example, cisplatin) (Perazella, 2009). These drugs induce their nephrotoxicity on the tubular, glomerular, interstitial or vascular components of the kidneys. Toxicity of drugs on renal tubular cells is enhanced by the impairment of mitochondrial function, tubular transport interference, increase in oxidative stress and formation of free radicals |
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| Cite Article: | "NEPHROTOXICITY", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 1, page no.a478-a479, January-2023, Available :http://www.ijnrd.org/papers/IJNRD2301055.pdf |
| Downloads: | 000118750 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2301055 Registration ID: 185657 Published In: Volume 8 Issue 1, January-2023 DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.32604 Page No: a478-a479 Country: jhajjar, Haryana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2301055 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2301055 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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